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韩国足月儿新生儿感染的危险因素。

Risk factors for neonatal infections in full-term babies in South Korea.

作者信息

Yoon Hye Sun, Shin Youn Jeong, Ki Moran

机构信息

Department of Pediatrics, Eulji Hospital, Seoul, Korea.

出版信息

Yonsei Med J. 2008 Aug 30;49(4):530-6. doi: 10.3349/ymj.2008.49.4.530.

Abstract

PURPOSE

Since 1997, private postnatal care facilities (San-hu-jo-ri-won in Korean) have emerged to take the role of the family. As a result, neonates are now exposed to many people and are very vulnerable to infection. However, there has been no study on the influence of postnatal care facilities on neonatal infection. The aim of this study was to determine the risk factors of neonatal infection in full-term babies in Korea.

MATERIALS AND METHODS

We followed up 556 pregnant women and their babies for 4 weeks after their births at 2 hospitals in Seoul and Daejeon from October 2004 to September 2005. Among 512 full-term babies, 58 had infectious diseases. To determine the risk factors for infection, 53 infected neonates at 4-28 days of life and 413 healthy neonates were compared.

RESULTS

The incidence of neonatal infection at 4 to 28 days after birth was 10.5%. After adjusting the related factors, the number of siblings (OR = 2.05, 95% CI = 1.13-3.71 for 1 or more) and postnatal care facilities or home aides (OR = 1.91, 95% CI = 1.07-3.45) were significant risk factors. Formula or mixed feeding (OR = 1.66, 95% CI = 0.91-3.04) increased the risk of neonatal infection but it was not statistically significant.

CONCLUSION

When the newborns had siblings, stayed at postnatal care facilities, or were cared for by home aides, the risk of neonatal infections significantly increased. Further research on the feeding effect on neonatal infection and evaluation of prevention efforts are needed.

摘要

目的

自1997年以来,私立产后护理机构(韩语称“三湖居里院”)开始承担起家庭的角色。结果,新生儿现在接触到很多人,极易受到感染。然而,尚未有关于产后护理机构对新生儿感染影响的研究。本研究的目的是确定韩国足月婴儿发生新生儿感染的危险因素。

材料与方法

2004年10月至2005年9月,我们在首尔和大田的2家医院对556名孕妇及其婴儿进行了出生后4周的随访。在512名足月婴儿中,58名患有传染病。为了确定感染的危险因素,对53名出生后4 - 28天的感染新生儿和413名健康新生儿进行了比较。

结果

出生后4至28天的新生儿感染发生率为10.5%。在调整相关因素后,兄弟姐妹的数量(1个或更多时,OR = 2.05,95%CI = 1.13 - 3.71)以及产后护理机构或家庭护理人员(OR = 1.91,95%CI = 1.07 - 3.45)是显著的危险因素。配方奶或混合喂养(OR = 1.66,95%CI = 0.91 - 3.04)增加了新生儿感染的风险,但无统计学意义。

结论

当新生儿有兄弟姐妹、住在产后护理机构或由家庭护理人员照顾时,新生儿感染的风险显著增加。需要进一步研究喂养对新生儿感染的影响以及评估预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9fa/2615279/bb5d2bf36c4f/ymj-49-530-g001.jpg

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