Luesink Maaike, Smeets Joep L R M, Brons Paul P T, Kapusta Livia
Pediatric Department, Radboud University Nijmegen Medical Center, Nijmegen the Netherlands.
Clin Pediatr (Phila). 2009 May;48(4):449-50. doi: 10.1177/0009922808323119. Epub 2008 Sep 4.
An 8-year-old girl who was recently diagnosed as having anaplastic large-cell lymphoma presented with atrial tachycardia and dilated cardiomyopathy, which is a contraindication for further treatment with cardio-toxic chemotherapy. After starting digoxin therapy, the dilated cardiomyopathy resolved. Repeated episodes of atrial tachycardia in this case were not caused by any common disorder but were due to mechanical stimulation by a central venous catheter. Central venous catheters are known to cause mainly ventricular arrhythmias. However, atrial tachycardia is a rare manifestation of arrhythmia due to mechanical stimulation of the heart by a central venous catheter, with potentially important cardiovascular consequences.
一名最近被诊断为间变性大细胞淋巴瘤的8岁女孩出现了房性心动过速和扩张型心肌病,这是进一步进行心脏毒性化疗的禁忌症。开始使用地高辛治疗后,扩张型心肌病得到缓解。该病例中反复出现的房性心动过速并非由任何常见疾病引起,而是由中心静脉导管的机械刺激所致。众所周知,中心静脉导管主要引起室性心律失常。然而,房性心动过速是中心静脉导管对心脏机械刺激导致的心律失常的罕见表现,可能会产生重要的心血管后果。