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[精神分裂症、强迫症以及伴有强迫症状的精神分裂症患者的比较]

[Comparison of patients with schizophrenia, obsessive-compulsive disorder, and schizophrenia with accompanying obsessive-compulsive symptoms].

作者信息

Güleç Gülcan, Güneş Elif, Yenilmez Cinar

出版信息

Turk Psikiyatri Derg. 2008 Fall;19(3):247-56.

Abstract

OBJECTIVE

The present study aimed to determine if schizophrenic patients with OC-symptoms represent a subtype of schizophrenia and to evaluate the differences between schizophrenic patients with OC symptoms and OCD patients.

METHODS

The study included 20 patients diagnosed with OCD, 40 schizophrenic patients, and 20 schizophrenic patients with OC symptoms. While the distribution and the severity of psychotic symptoms in the OC-schizophrenia group were compared to those of the schizophrenic patients, and while the distribution and severity of obsessive-compulsive symptoms of the OC-schizophrenia group were compared to OCD patients, all 3 groups were compared to each other in terms of demographic data and other clinical characteristics.

RESULTS

There were no differences in the distribution and severity of psychotic symptoms between the OC-schizophrenia group and the schizophrenia group. Moreover, the distribution and severity of OC symptoms in the OC-schizophrenia group were no different than those in the OCD group. Brief Disability Questionnaire scores were significantly higher in the OC-schizophrenia group than in the other 2 groups. Hamilton Depression Scale and Hamilton Anxiety Scale mean scores were significantly higher in the OCD and OC-schizophrenia groups than in the schizophrenia group. Moreover, Yale-Brown Obsessive-Compulsive Scale total scores were not correlated to the Scale for the Assessment of Negative Symptoms or the Scale for the Assessment of Positive Symptoms scores in the OC-schizophrenia group.

CONCLUSION

According to our results OC-schizophrenia might be a sub-type of schizophrenia, which doesn't have more severe psychotic symptoms, but more severe depression and anxiety, which are related to greater disability.

摘要

目的

本研究旨在确定伴有强迫症状的精神分裂症患者是否代表精神分裂症的一个亚型,并评估伴有强迫症状的精神分裂症患者与强迫症患者之间的差异。

方法

该研究纳入了20名被诊断为强迫症的患者、40名精神分裂症患者以及20名伴有强迫症状的精神分裂症患者。将强迫症状型精神分裂症组的精神病性症状的分布及严重程度与精神分裂症患者的进行比较,同时将强迫症状型精神分裂症组的强迫症状的分布及严重程度与强迫症患者的进行比较,并且在人口统计学数据和其他临床特征方面对所有三组进行相互比较。

结果

强迫症状型精神分裂症组与精神分裂症组在精神病性症状的分布及严重程度上没有差异。此外,强迫症状型精神分裂症组中强迫症状的分布及严重程度与强迫症组的并无不同。强迫症状型精神分裂症组的简易残疾问卷得分显著高于其他两组。强迫症组和强迫症状型精神分裂症组的汉密尔顿抑郁量表和汉密尔顿焦虑量表平均得分显著高于精神分裂症组。此外,在强迫症状型精神分裂症组中,耶鲁-布朗强迫量表总分与阴性症状评估量表或阳性症状评估量表得分不相关。

结论

根据我们的研究结果,强迫症状型精神分裂症可能是精神分裂症的一个亚型,其没有更严重的精神病性症状,但有更严重的抑郁和焦虑,这与更大的残疾相关。

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