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乳腺癌患者及其伴侣与匹配对照夫妻的痛苦历程。

Course of distress in breast cancer patients, their partners, and matched control couples.

作者信息

Hinnen Chris, Ranchor Adelita V, Sanderman Robbert, Snijders Tom A B, Hagedoorn Mariët, Coyne James C

机构信息

Department of Health Sciences, Graduate School for Health Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

出版信息

Ann Behav Med. 2008 Oct;36(2):141-8. doi: 10.1007/s12160-008-9061-8. Epub 2008 Sep 17.

Abstract

BACKGROUND

Previous studies offer a limited perspective on the dynamic course of distress in cancer patients and their partners, owing to a restricted number of assessment points and the absence of comparison controls drawn from the general population.

PURPOSE

This study investigated the course of distress among breast cancer patients and their partners (N = 92 couples) in comparison to matched control couples (N = 64). Furthermore, the influence of neuroticism on distress was investigated.

METHOD

The Hospital Anxiety and Depression Scale was administered nine times over a 12-month period, and neuroticism was assessed at the beginning of the study using the Eysenck Personality Questionnaire.

RESULTS

Multilevel analyses revealed that patients were more distressed during the first 15 months after diagnosis than nonpatients. A significant portion of the distress that could not be explained by the cancer experience was explained by neuroticism.

CONCLUSION

Differences in distress between patients and comparison-control women are relatively small and decreased over time, while distress in male partners was not elevated in comparison to their controls.

摘要

背景

由于评估点数量有限且缺乏来自普通人群的对照,以往研究对癌症患者及其伴侣痛苦的动态过程提供的视角有限。

目的

本研究调查了乳腺癌患者及其伴侣(92对夫妻)与匹配的对照夫妻(64对)相比痛苦的过程。此外,还研究了神经质对痛苦的影响。

方法

在12个月内对医院焦虑抑郁量表进行了9次施测,并在研究开始时使用艾森克人格问卷评估神经质。

结果

多层次分析显示,患者在诊断后的前15个月比非患者更痛苦。无法用癌症经历解释的痛苦的很大一部分可由神经质来解释。

结论

患者与对照女性之间的痛苦差异相对较小且随时间减少,而男性伴侣的痛苦与对照组相比并未升高。

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