Njoroge G K, Njagi E N M, Orinda G O, Sekadde-Kigondu C B, Kayima J K
Department of Laboratory Medicine, Intensive Care Unit, Kenyatta National Hospital, P.O. Box 20723, Nairobi, Kenya.
East Afr Med J. 2008 Jun;85(6):284-91. doi: 10.4314/eamj.v85i6.9626.
To determine the status of environmental and occupational lead exposure in selected areas in Nairobi, Kenya.
Cross sectional study.
Kariobangi North, Babadogo, Waithaka and Pumwani for assessment of environmental exposure to lead (Pb) and Ziwani Jua Kali works for assessment of occupational lead exposure. Olkalou in Nyandarua District was the covariate study area.
Three hundred and eight children and adults participated.
Blood lead levels (BLLs) obtained for the entire sample (n = 308) ranged from 0.4 to 65 microg/dl of blood. One hundred and sixty nine (55%) of the total sample had levels equal to or below 4.9 microg/dl, while 62 (20%) of the sample had levels ranging from 5.0 to 9.9 microg/dl. Blood lead levels above 10 microg/dl were recorded in 77 (25%) of the total sample. Within Nairobi, 32 (15.3%) of the study subjects in areas meant for assessment of environmental lead exposure had levels above the WHO/CDC action levels of 10 microg/dl of blood. The mean BLL for the occupationally exposed (Ziwani Jua kali) was 22.6 +/- 13.4 microg/dl. Among the workers, 89% had BLLs above 10 microg/dl. In general, 15% of the entire sample (for both environmental and occupational groups) in Nairobi had BLLs above 15 microg/dl. The covariate group at Olkalou had a mean BLL of 1.3 +/- 0.9 microg/dl.
The prevalence of environmental lead exposure to the general public is high in Nairobi compared to Olkalou where non exposure was reported. Occupational lead exposure has been identified to be at alarming levels and urgent intervention measures are recommended.
确定肯尼亚内罗毕选定地区的环境和职业铅暴露状况。
横断面研究。
卡里奥班吉北区、巴巴多戈、韦萨卡和普姆瓦尼用于评估环境铅暴露,齐瓦尼朱阿卡里工厂用于评估职业铅暴露。恩延达鲁瓦区的奥尔卡洛为对照研究地区。
308名儿童和成人参与。
整个样本(n = 308)的血铅水平(BLLs)范围为每分升血液0.4至65微克。总样本中有169人(55%)的血铅水平等于或低于4.9微克/分升,而样本中有62人(20%)的血铅水平在5.0至9.9微克/分升之间。总样本中有77人(25%)的血铅水平高于10微克/分升。在内罗毕,用于评估环境铅暴露地区的32名(15.3%)研究对象的血铅水平高于世界卫生组织/美国疾病控制与预防中心每分升血液10微克的行动水平。职业暴露组(齐瓦尼朱阿卡里工厂)的平均血铅水平为22.6±13.4微克/分升。在工人中,89%的人血铅水平高于10微克/分升。总体而言,内罗毕整个样本(环境和职业组)中有15%的人血铅水平高于15微克/分升。奥尔卡洛的对照组成员平均血铅水平为1.3±0.9微克/分升。
与报告无铅暴露的奥尔卡洛相比,内罗毕普通公众的环境铅暴露患病率较高。已确定职业铅暴露处于惊人水平,建议采取紧急干预措施。