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两例自身免疫性胰腺炎合并硬化性胆管炎患者的肝脏萎缩和门静脉狭窄

Liver atrophy and portal stenosis in two cases of sclerosing cholangitis associated with autoimmune pancreatitis.

作者信息

Hirano Atsuyuki, Nakazawa Takahiro, Ohara Hirotaka, Ando Tomoaki, Hayashi Kazuki, Tanaka Hajime, Naito Itaru, Okumura Fumihiro, Yokoyama Yoshifumi, Joh Takashi

机构信息

Department of Internal Medicine, Nagoya Higashi Municipal Hospital.

出版信息

Intern Med. 2008;47(19):1689-94. doi: 10.2169/internalmedicine.47.1192. Epub 2008 Oct 1.

Abstract

Sclerosing cholangitis with autoimmune pancreatitis (SC with AIP) takes a better clinical course than primary sclerosing cholangitis due to the effectiveness of steroid therapy. However, the morphological and functional changes in SC with AIP during long-term observation have not yet been reported. We encountered two cases of SC with AIP that resulted in liver atrophy and portal obstruction during long-term observation. One case was followed up without steroid therapy. The other case was treated with endoscopic biliary drainage initially. These cases may provide further information regarding steroid therapy for SC with AIP.

摘要

自身免疫性胰腺炎合并硬化性胆管炎(SC合并AIP)由于类固醇治疗的有效性,其临床病程比原发性硬化性胆管炎更好。然而,长期观察期间SC合并AIP的形态学和功能变化尚未见报道。我们遇到两例SC合并AIP患者,在长期观察中出现了肝萎缩和门静脉梗阻。一例未接受类固醇治疗进行随访。另一例最初接受了内镜胆管引流治疗。这些病例可能为SC合并AIP的类固醇治疗提供更多信息。

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