Manabe Ryuji, Kunugita Naoki, Katoh Takahiko, Kuroda Yoshiki, Akiyama Yukio, Yamano Yuko, Uchiyama Iwao, Arashidani Keiichi
Division of Public Health, Department of Social Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Nihon Eiseigaku Zasshi. 2008 Jul;63(4):717-23. doi: 10.1265/jjh.63.717.
The purpose of this study was to investigate the incidence of multiple chemical sensitivity (MCS) and effectiveness of the Quick Environment Exposure and Sensitivity Inventory (QEESI) in Japanese workers in specific buildings.
The survey was performed in 2004-2006 in Japan. QEESI (Japanese version) and a checklist on accumulation of fatigue developed by the Ministry of Health, Labour and Welfare were used in the examination of 410 workers in specific buildings. Three criteria of QEESI's "symptom severity", "chemical intolerance", and "other intolerance" were evaluated in this study. Clinical histories were also surveyed.
Responses were obtained from 368 (89.8%) workers. The results showed that 132 (35.9%) individuals have been diagnosed as having allergy. Only two (0.5%) individuals were found to be MCS patients. There was no sick building syndrome patient. Applying the "high" criteria with QEESI to the standard of Miller and Ashford, we determined that only four (1.1%) individuals met all the three criteria, and 17 (4.6%) individuals met two of the three criteria. The QEESI score of allergy persons was higher than that of nonallergy persons. Among nonallergy persons, those who have a high score on accumulation of fatigue in the checklist showed a high score in QESSI.
These findings indicated that the QEESI score tended to increase with workload and be high in individuals with allergy. Therefore, careful consideration is required, when QEESI is applied for screening MCS patients in Japan.
本研究旨在调查日本特定建筑内工人多重化学物质敏感症(MCS)的发病率以及快速环境暴露与敏感症量表(QEESI)的有效性。
该调查于2004年至2006年在日本进行。在对特定建筑内的410名工人进行检查时,使用了QEESI(日文版)以及厚生劳动省制定的疲劳积累检查表。本研究评估了QEESI的“症状严重程度”“化学不耐受”和“其他不耐受”三个标准。还调查了临床病史。
368名(89.8%)工人进行了回复。结果显示,132名(35.9%)个体被诊断患有过敏症。仅发现两名(0.5%)个体为MCS患者。未发现病态建筑综合征患者。将QEESI的“高”标准应用于米勒和阿什福德的标准,我们确定只有四名(1.1%)个体符合所有三个标准,17名(4.6%)个体符合三个标准中的两个。过敏者的QEESI得分高于非过敏者。在非过敏者中,检查表中疲劳积累得分高的人在QEESI中得分也高。
这些发现表明,QEESI得分往往随着工作量增加而升高,且在过敏个体中较高。因此,在日本将QEESI用于筛查MCS患者时需要谨慎考虑。