Simopoulos Thomas T, Kraemer Jan J, Glazer Paul, Bajwa Zahid H
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Pain Physician. 2008 Sep-Oct;11(5):693-7.
Epidural steroid injections are commonly used to palliate the symptoms of spinal stenosis. Deep tissue infection is a known potential complication of these injections. There have been no previous published cases of osteomyelitis without epidural abscess after such injections. We present a case in an elderly patient who presented only with persistent axial low back pain following a lumbar epidural steroid injection (LESI). We emphasize early patient evaluation, consideration of infectious predisposing factors, sterile technique, and skin disinfectant.
Open-label case report.
A 77-year-old diabetic male with a history of radicular pain related to lumbar spinal stenosis was treated successfully several years prior with a series of lumbar epidural steroid injections (LESI) and was re-treated with LESIs for recurrent symptoms. Following his second epidural injection, he presented with back pain and induration at the injection site without fever or neurological deficits. Urgent magnetic resonance imaging (MRI) revealed a soft tissue abscess extending close to the epidural space around the corresponding L4/L5 vertebral level. The patient recovered after incision and drainage of the abscess which was associated with an osteomyelitis of the L4 and L5 vertebral spine. The causative organism was methicillin-resistant Staphylococcus Aureus.
This case demonstrates that even with proper aseptic techniques, immune-compromised patients who are colonized with an aggressive micro-organism may develop a potentially catastrophic infectious complication if subtle persistent symptomatic complaints are not promptly and carefully evaluated.
硬膜外类固醇注射常用于缓解椎管狭窄症状。深部组织感染是这些注射已知的潜在并发症。此前尚无此类注射后发生无硬膜外脓肿的骨髓炎的病例报道。我们报告一例老年患者,其在接受腰椎硬膜外类固醇注射(LESI)后仅出现持续性轴向腰痛。我们强调早期患者评估、对感染易感因素的考虑、无菌技术及皮肤消毒剂的使用。
开放标签病例报告。
一名77岁男性糖尿病患者,有与腰椎管狭窄相关的神经根性疼痛病史,数年前曾成功接受一系列腰椎硬膜外类固醇注射(LESI)治疗,此次因症状复发再次接受LESI治疗。第二次硬膜外注射后,他出现注射部位背痛及硬结,无发热或神经功能缺损。紧急磁共振成像(MRI)显示在相应L4/L5椎体水平附近有一个软组织脓肿延伸至硬膜外间隙。患者在脓肿切开引流后康复,该脓肿与L4和L5椎体骨髓炎相关。致病微生物为耐甲氧西林金黄色葡萄球菌。
本病例表明,即使采用了适当的无菌技术,若对细微的持续性症状性主诉未及时、仔细评估,携带侵袭性微生物的免疫功能低下患者仍可能发生潜在灾难性感染并发症。