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本文引用的文献

1
Variations in the associations between psychiatric comorbidity and hospital mortality according to the method of identifying psychiatric diagnoses.根据精神疾病诊断识别方法,精神疾病合并症与医院死亡率之间关联的差异。
J Gen Intern Med. 2008 Mar;23(3):317-22. doi: 10.1007/s11606-008-0518-z. Epub 2008 Jan 23.
2
Risk of malignancy in patients with schizophrenia or bipolar disorder: nested case-control study.精神分裂症或双相情感障碍患者的恶性肿瘤风险:巢式病例对照研究。
Arch Gen Psychiatry. 2007 Dec;64(12):1368-76. doi: 10.1001/archpsyc.64.12.1368.
3
Increased mortality among patients admitted with major psychiatric disorders: a register-based study comparing mortality in unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder, and schizophrenia.患有重度精神疾病的入院患者死亡率增加:一项基于登记数据的研究,比较单相抑郁症、双相情感障碍、分裂情感性障碍和精神分裂症患者的死亡率。
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Metabolic syndrome and the risk of coronary heart disease in 367 patients treated with second-generation antipsychotic drugs.367例使用第二代抗精神病药物治疗患者的代谢综合征与冠心病风险
J Clin Psychiatry. 2006 Apr;67(4):575-83. doi: 10.4088/jcp.v67n0408.
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A randomized clinical trial of a new behavioral treatment for drug abuse in people with severe and persistent mental illness.一项针对患有严重和持续性精神疾病的药物滥用者的新型行为治疗的随机临床试验。
Arch Gen Psychiatry. 2006 Apr;63(4):426-32. doi: 10.1001/archpsyc.63.4.426.
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Risk for coronary heart disease in people with severe mental illness: cross-sectional comparative study in primary care.重度精神疾病患者的冠心病风险:初级保健中的横断面比较研究
Br J Psychiatry. 2006 Mar;188:271-7. doi: 10.1192/bjp.bp.104.008060.
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Schizophrenia, neuroleptic medication and mortality.精神分裂症、抗精神病药物与死亡率
Br J Psychiatry. 2006 Feb;188:122-7. doi: 10.1192/bjp.188.2.122.
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Improving the care of individuals with schizophrenia and substance use disorders: consensus recommendations.改善精神分裂症和物质使用障碍患者的护理:共识性建议。
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瑞典严重精神障碍患者的超额死亡率:一项对12103名有或无精神科服务接触史个体的队列研究。

Excess mortality in persons with severe mental disorder in Sweden: a cohort study of 12 103 individuals with and without contact with psychiatric services.

作者信息

Tidemalm Dag, Waern Margda, Stefansson Claes-Göran, Elofsson Stig, Runeson Bo

机构信息

Department of Clinical Neuroscience, Karolinska Institutet, Division of Psychiatry St, Göran Hospital, Vårdvägen 3, SE-112 81 Stockholm, Sweden.

出版信息

Clin Pract Epidemiol Ment Health. 2008 Oct 14;4:23. doi: 10.1186/1745-0179-4-23.

DOI:10.1186/1745-0179-4-23
PMID:18854034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2576252/
Abstract

BACKGROUND

Investigating mortality in those with mental disorder is one way of measuring effects of mental health care reorganisation. This study's aim was to investigate whether the excess mortality in those with severe mental disorder remains high in Sweden after the initiation of the Community Mental Health Care Reform. We analysed excess mortality by gender, type of mental health service and psychiatric diagnosis in a large community-based cohort with long-term mental disorder.

METHODS

A survey was conducted in Stockholm County, Sweden in 1997 to identify adults with long-term disabling mental disorder (mental retardation and dementia excluded). The 12 103 cases were linked to the Hospital Discharge Register and the Cause of Death Register. Standardised mortality ratios (SMRs) for 1998-2000 were calculated for all causes of death, in the entire cohort and in subgroups based on treatment setting and diagnosis.

RESULTS

Mortality was increased in both genders, for natural and external causes and in all diagnostic subgroups. Excess mortality was greater among those with a history of psychiatric inpatient care, especially in those with substance use disorder. For the entire cohort, the number of excess deaths due to natural causes was threefold that due to external causes. SMRs in those in contact with psychiatric services where strikingly similar to those in contact with social services.

CONCLUSION

Mortality remains high in those with long-term mental disorder in Sweden, regardless of treatment setting. Treatment programs for persons with long-term mental disorder should target physical as well as mental health.

摘要

背景

调查精神障碍患者的死亡率是衡量精神卫生保健重组效果的一种方式。本研究的目的是调查在社区精神卫生保健改革启动后,瑞典重度精神障碍患者的超额死亡率是否仍然很高。我们在一个患有长期精神障碍的大型社区队列中,按性别、精神卫生服务类型和精神科诊断分析了超额死亡率。

方法

1997年在瑞典斯德哥尔摩县进行了一项调查,以确定患有长期致残性精神障碍(不包括智力发育迟缓及痴呆)的成年人。12103例病例与医院出院登记册和死亡原因登记册相链接。计算了1998 - 2000年整个队列以及基于治疗环境和诊断的亚组中所有死因的标准化死亡率(SMR)。

结果

男女两性在自然和外部原因导致的死亡以及所有诊断亚组中的死亡率均有所上升。有精神科住院治疗史的患者超额死亡率更高,尤其是患有物质使用障碍的患者。对于整个队列,自然原因导致的超额死亡人数是外部原因导致的超额死亡人数的三倍。与精神科服务接触者的标准化死亡率与与社会服务接触者的标准化死亡率惊人地相似。

结论

在瑞典,患有长期精神障碍的患者死亡率仍然很高,无论治疗环境如何。针对长期精神障碍患者的治疗方案应同时关注身心健康。