自闭症：定义、神经生物学、筛查与诊断
Autism: definition, neurobiology, screening, diagnosis.
作者信息
Rapin Isabelle, Tuchman Roberto F
机构信息
Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
出版信息
Pediatr Clin North Am. 2008 Oct;55(5):1129-46, viii. doi: 10.1016/j.pcl.2008.07.005.
Autism (ie, the autism spectrum disorders) is now recognized in 1 in 150 children. This article highlights the definition, neurobiology, screening, and diagnosis of autism. The genetics, immunology, imaging, and neurophysiology of autism are reviewed, with particular emphasis on areas that impact pediatricians. Early recognition of the social deficits that characterize autism is key to maximizing the potential of these children.
如今，每150名儿童中就有1人被诊断患有自闭症（即自闭症谱系障碍）。本文重点介绍自闭症的定义、神经生物学、筛查及诊断。文中回顾了自闭症的遗传学、免疫学、影像学及神经生理学，尤其着重于对儿科医生有影响的领域。尽早识别自闭症所特有的社交缺陷，是使这些儿童的潜力得到最大发挥的关键。
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