Wenzel Richard P, Bearman Gonzalo, Edmond Michael B
Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia, USA.
Infect Control Hosp Epidemiol. 2008 Nov;29(11):1012-8. doi: 10.1086/593120.
Focusing hospital resources on a single antibiotic-resistant pathogen as a sole approach to infection control is inherently flawed. We applied attributable mortality principles to a basic model of bloodstream infections to outline the argument. Screening for methicillin-resistant Staphylococcus aureus alone made sense in the 1980s, but the ongoing emergence of vancomycin-resistant enterococci and antibiotic-resistant strains of gram-negative rods and Candida species, as well as the recognition of the value of team-based infection control programs, support a population-based approach.
将医院资源仅集中于单一的耐药病原体作为感染控制的唯一方法,本质上是有缺陷的。我们将归因死亡率原则应用于血流感染的基本模型来阐述这一观点。在20世纪80年代,仅筛查耐甲氧西林金黄色葡萄球菌是有意义的,但耐万古霉素肠球菌、革兰氏阴性杆菌和念珠菌属的耐药菌株不断出现,以及对基于团队的感染控制项目价值的认识,都支持采用基于人群的方法。