Meier Iris, Brkljacic Jelena
Department of Plant Cellular and Molecular Biology, Plant Biotechnology Center, Ohio State University, Columbus, OH 43210, USA.
Curr Opin Plant Biol. 2009 Feb;12(1):87-95. doi: 10.1016/j.pbi.2008.09.001. Epub 2008 Oct 19.
All macromolecules that traffic between the nucleus and the cytoplasm traverse the nuclear pore. While yeast and mammalian nuclear pore structure and function have recently been substantially refined, our understanding of the plant nuclear pore is still far from comprehensive. Nevertheless, a number of nuclear pore and nucleocytoplasmic trafficking components have recently been identified as required for diverse developmental and signaling pathways. In addition, some aspects of the nuclear pore composition itself now appear under developmental control and nuclear pore components have recently surfaced as novel players in plant cytokinesis. Here, we review these new findings in context and attempt to correlate molecular functions with developmental processes.
所有在细胞核与细胞质之间运输的大分子都要穿过核孔。虽然酵母和哺乳动物的核孔结构与功能最近已得到大幅完善,但我们对植物核孔的了解仍远不够全面。然而,最近已鉴定出许多核孔和核质运输组件是多种发育和信号通路所必需的。此外,核孔组成本身的某些方面现在似乎受发育调控,并且核孔组件最近已成为植物胞质分裂中的新角色。在此,我们结合背景回顾这些新发现,并尝试将分子功能与发育过程联系起来。