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RNA in motion.运动中的RNA
Curr Opin Chem Biol. 2008 Dec;12(6):612-8. doi: 10.1016/j.cbpa.2008.09.033. Epub 2008 Oct 26.
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13C NMR relaxation studies of RNA base and ribose nuclei reveal a complex pattern of motions in the RNA binding site for human U1A protein.对RNA碱基和核糖核进行的13C NMR弛豫研究揭示了人类U1A蛋白RNA结合位点中复杂的运动模式。
J Mol Biol. 2005 Jun 17;349(4):699-715. doi: 10.1016/j.jmb.2005.04.012. Epub 2005 Apr 21.
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RNA Dynamics by NMR Spectroscopy.通过 NMR 光谱学研究 RNA 的动态变化。
Chembiochem. 2019 Nov 4;20(21):2685-2710. doi: 10.1002/cbic.201900072. Epub 2019 Jul 17.
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NMR studies of dynamics in RNA and DNA by 13C relaxation.通过碳-13弛豫对RNA和DNA动力学进行的核磁共振研究。
Biopolymers. 2007;86(5-6):348-59. doi: 10.1002/bip.20650.
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Examining the relationship between RNA function and motion using nuclear magnetic resonance.使用核磁共振技术研究 RNA 功能与运动之间的关系。
Wiley Interdiscip Rev RNA. 2012 Jan-Feb;3(1):122-32. doi: 10.1002/wrna.108. Epub 2011 Aug 17.
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Selecting apt RNAs for NMR.为核磁共振选择合适的核糖核酸。
RNA. 1996 Jul;2(7):625-7.
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Functional complexity and regulation through RNA dynamics.通过 RNA 动态实现功能复杂性和调控。
Nature. 2012 Feb 15;482(7385):322-30. doi: 10.1038/nature10885.
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Binding of U1A protein changes RNA dynamics as observed by 13C NMR relaxation studies.通过13C NMR弛豫研究观察到，U1A蛋白的结合会改变RNA动力学。
Biochemistry. 2007 May 22;46(20):5875-83. doi: 10.1021/bi602658x. Epub 2007 May 1.
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NMR spectroscopy of RNA.RNA的核磁共振光谱学。
Chembiochem. 2003 Oct 6;4(10):936-62. doi: 10.1002/cbic.200300700.
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Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition?[Rp]-和[Sp]-硫代磷酸化DNA-RNA杂交体的动态核磁共振结构：核糖核酸酶H识别是否需要灵活性？
Biophys J. 2003 Oct;85(4):2525-38. doi: 10.1016/S0006-3495(03)74675-X.
引用本文的文献
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and Evaluation of the Pathology and Safety Aspects of Three- and Four-Way Junction RNA Nanoparticles.并评估三向和四向连接 RNA 纳米颗粒的病理学和安全性方面。
Mol Pharm. 2024 Feb 5;21(2):718-728. doi: 10.1021/acs.molpharmaceut.3c00845. Epub 2024 Jan 12.
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Biomotors, viral assembly, and RNA nanobiotechnology: Current achievements and future directions.生物马达、病毒组装与RNA纳米生物技术：当前成就与未来方向
Comput Struct Biotechnol J. 2022 Nov 11;20:6120-6137. doi: 10.1016/j.csbj.2022.11.007. eCollection 2022.
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The dynamic, motile and deformative properties of RNA nanoparticles facilitate the third milestone of drug development.RNA 纳米颗粒的动态、运动和变形特性促进了药物开发的第三个里程碑。
Adv Drug Deliv Rev. 2022 Jul;186:114316. doi: 10.1016/j.addr.2022.114316. Epub 2022 May 5.
4
Target-Directed Approaches for Screening Small Molecules against RNA Targets.靶向 RNA 靶标的小分子筛选的目标导向方法。
SLAS Discov. 2020 Sep;25(8):869-894. doi: 10.1177/2472555220922802. Epub 2020 May 18.
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Fluorescence-based tools to probe G-quadruplexes in cell-free and cellular environments.用于在无细胞和细胞环境中探测G-四链体的基于荧光的工具。
RSC Adv. 2018;8(45):25673-25694. doi: 10.1039/C8RA03708F. Epub 2018 Jul 17.
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Saturation of recognition elements blocks evolution of new tRNA identities.识别元件的饱和会阻碍新tRNA身份的进化。
Sci Adv. 2016 Apr 29;2(4):e1501860. doi: 10.1126/sciadv.1501860. eCollection 2016 Apr.
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Integrating molecular dynamics simulations with chemical probing experiments using SHAPE-FIT.使用SHAPE-FIT将分子动力学模拟与化学探测实验相结合。
Methods Enzymol. 2015;553:215-34. doi: 10.1016/bs.mie.2014.10.061. Epub 2015 Feb 7.
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Dynamics of riboswitches: Molecular simulations.核糖开关的动力学：分子模拟
Biochim Biophys Acta. 2014 Oct;1839(10):1046-1050. doi: 10.1016/j.bbagrm.2014.06.010. Epub 2014 Jun 19.
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Roles of long-range tertiary interactions in limiting dynamics of the Tetrahymena group I ribozyme.远距离三级相互作用在限制嗜热四膜虫I组核酶动力学中的作用。
J Am Chem Soc. 2014 May 7;136(18):6643-8. doi: 10.1021/ja413033d. Epub 2014 Apr 28.
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Molecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structure.利用原始 NMR 数据对两种不同的小 RNA 环结构进行分子动力学重新精修，提示出一种共同的结构。
J Biomol NMR. 2012 Aug;53(4):321-39. doi: 10.1007/s10858-012-9642-5. Epub 2012 Jun 20.
本文引用的文献
1
NMR and MD studies of the temperature-dependent dynamics of RNA YNMG-tetraloops.RNA YNMG四环温度依赖动力学的核磁共振与分子动力学研究
Nucleic Acids Res. 2008 Apr;36(6):1928-40. doi: 10.1093/nar/gkm1183. Epub 2008 Feb 13.
2
Simulation of the pressure and temperature folding/unfolding equilibrium of a small RNA hairpin.小RNA发夹结构的压力和温度折叠/去折叠平衡模拟
J Am Chem Soc. 2008 Jan 23;130(3):815-7. doi: 10.1021/ja074191i. Epub 2007 Dec 23.
3
Visualizing spatially correlated dynamics that directs RNA conformational transitions.可视化指导RNA构象转变的空间相关动力学。
Nature. 2007 Dec 20;450(7173):1263-7. doi: 10.1038/nature06389.
4
Molecular dynamics simulation of the structure, dynamics, and thermostability of the RNA hairpins uCACGg and cUUCGg.RNA发夹uCACGg和cUUCGg的结构、动力学及热稳定性的分子动力学模拟
J Phys Chem B. 2008 Jan 10;112(1):134-42. doi: 10.1021/jp0764337. Epub 2007 Dec 11.
5
Dynamics of large elongated RNA by NMR carbon relaxation.通过核磁共振碳弛豫研究大型细长RNA的动力学
J Am Chem Soc. 2007 Dec 26;129(51):16072-82. doi: 10.1021/ja0757982. Epub 2007 Nov 30.
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Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: analysis of L11 movements.嗜盐嗜碱菌大核糖体亚基L7/L12柄基部结构：L11运动分析
J Mol Biol. 2007 Aug 24;371(4):1047-59. doi: 10.1016/j.jmb.2007.05.091. Epub 2007 Jun 4.
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Elastic properties of ribosomal RNA building blocks: molecular dynamics of the GTPase-associated center rRNA.核糖体RNA构建模块的弹性特性：GTP酶相关中心rRNA的分子动力学
Nucleic Acids Res. 2007;35(12):4007-17. doi: 10.1093/nar/gkm245. Epub 2007 Jun 6.
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iRED analysis of TAR RNA reveals motional coupling, long-range correlations, and a dynamical hinge.TAR RNA的红外光谱分析揭示了运动耦合、长程相关性和一个动态铰链。
Biophys J. 2007 Jul 15;93(2):411-22. doi: 10.1529/biophysj.107.104620. Epub 2007 Apr 20.
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Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers.用于核酸的AMBER力场的优化：改进α/γ构象异构体的描述。
Biophys J. 2007 Jun 1;92(11):3817-29. doi: 10.1529/biophysj.106.097782. Epub 2007 Mar 9.
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Resolving fast and slow motions in the internal loop containing stem-loop 1 of HIV-1 that are modulated by Mg2+ binding: role in the kissing-duplex structural transition.解析HIV-1中包含茎环1的内环中由Mg2+结合调节的快速和慢速运动：在亲吻双链体结构转变中的作用。
Nucleic Acids Res. 2007;35(5):1698-713. doi: 10.1093/nar/gkm020. Epub 2007 Feb 20.
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