Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands.
Neth Heart J. 2008 Oct;16(Suppl 1):S25-7.
In patients with sick sinus syndrome and normal atrioventricular conduction, physiological pacing can be accomplished with either a single chamber atrial pacemaker AAI/R or a dual chamber pacemaker DDD/R. The single chamber device has the advantages of simpler implantation and lower initial costs, while the dual chamber device offers protection in case atrioventricular conduction disturbances develop in the future. When rigorous attention is paid to the pre-implantation selection criteria, the incidence of reported second- or third-degree atrioventricular block varied between 0.4 and 1.8% per annum. Medical practice, however, has shifted to predominant implantation of DDD/R pacemakers in more than 95% of patients with sick sinus syndrome. Recent publications have reported an increase in left atrial diameter, decrease in left ventricular fractional shortening and increased incidence of atrial fibrillation in patients with DDD/R pacing as compared with patients with single chamber atrial devices. These changes were proportional to the percentage of ventricular paced beats.New algorithms in dual chamber devices have been developed in order to minimise ventricular stimulation. These are being evaluated at present. In my opinion there is still a place for atrial pacing in selected patients with sick sinus syndrome with a minimum risk of developing complete atrioventricular block. (Neth Heart J 2008;16(Suppl1):S25-S27.).
在病态窦房结综合征且房室传导正常的患者中,生理性起搏可通过单腔心房起搏器(AAI/R)或双腔起搏器(DDD/R)实现。单腔器械具有植入更简单、初始成本更低的优势,而双腔器械则为未来可能发生的房室传导障碍提供了保护。如果在植入前仔细选择适应证,报告的二度或三度房室传导阻滞发生率为每年 0.4%至 1.8%。然而,临床实践已转向在超过 95%的病态窦房结综合征患者中主要植入 DDD/R 起搏器。最近的出版物报道,与单腔心房器械相比,DDD/R 起搏患者的左心房直径增大、左心室短轴缩短分数降低和心房颤动发生率增加。这些变化与心室起搏的比例成正比。为了尽量减少心室刺激,双腔器械中已开发出新的算法。目前正在对这些算法进行评估。依我之见,在发生完全性房室传导阻滞风险最小的特定病态窦房结综合征患者中,仍有应用心房起搏的一席之地。(Neth Heart J 2008;16(Suppl1):S25-S27.)。