Semoun O, Guigui B, Tick S, Coscas G, Soubrane G, Souied E H
Service Universitaire d'Ophtalmologie de Créteil, Université Paris 12, Faculté de médecine Henri Mondor, Centre Hospitalier Intercommunal de Créteil, Créteil, France.
Br J Ophthalmol. 2009 Feb;93(2):182-5. doi: 10.1136/bjo.2008.145235. Epub 2008 Nov 4.
Wet age-related macular degeneration (AMD) represents a heterogeneous group of phenotypes, all defined by fluorescein angiography features (FA). Imaging of wet AMD is extensively described in literature, including colour pictures, FA, indocyanine green angiography (ICG) and optical coherence tomography (OCT). The purpose of this study was to describe features of infrared (IR) pictures of a homogeneous subgroup of classic choroidal neovascularisation (CNV) associated with wet AMD, METHODS: We analysed 22 eyes of 22 consecutive patients with classic CNV. All patients underwent a complete ophthalmological examination including colour fundus photography, infrared picture, fluorescein angiography, indocyanine green angiography and an optical coherence tomography.
Infrared pictures revealed a whitish ring surrounding the neovascular lesion in all eyes (22/22). The whitish ring corresponded in all cases to the borders of the CNV defined on the early phase of FA and ICG pictures. The ring had an "O-shape" in 15/22 cases (68%) and a "U-shape" in 7/22 cases (32%).
Analysis of infrared pictures in classic CNV constantly revealed a whitish ring that is correlated to the limits of the lesion. IR picture is a non invasive imaging of the macula, but the specificity of the features needs to be investigated in further studies.
湿性年龄相关性黄斑变性(AMD)代表一组异质性表型,均由荧光素血管造影特征(FA)定义。湿性AMD的影像学在文献中有广泛描述,包括彩色图片、FA、吲哚菁绿血管造影(ICG)和光学相干断层扫描(OCT)。本研究的目的是描述与湿性AMD相关的典型脉络膜新生血管(CNV)同质亚组的红外(IR)图片特征。
我们分析了22例连续患有典型CNV患者的22只眼。所有患者均接受了全面的眼科检查,包括彩色眼底照相、红外图片、荧光素血管造影、吲哚菁绿血管造影和光学相干断层扫描。
红外图片显示所有眼中(22/22)新生血管病变周围有白色环。在所有病例中,白色环均与FA和ICG图片早期定义的CNV边界相对应。该环在15/22例(68%)中呈“O形”,在7/22例(32%)中呈“U形”。
对典型CNV的红外图片分析始终显示出与病变边界相关的白色环。IR图片是黄斑的一种非侵入性成像,但这些特征的特异性需要在进一步研究中进行调查。