Carlino Mauro, Godino Cosmo, Latib Azeem, Moses Jeffrey W, Colombo Antonio
Interventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Catheter Cardiovasc Interv. 2008 Nov 15;72(6):790-6. doi: 10.1002/ccd.21699.
To assess the procedural and clinical outcomes from a modified subintimal tracking and re-entry (STAR) procedure performed using contrast guidance.
Previous data showed that recanalizing a chronic total occlusion (CTO) with the STAR technique was possible. However, this technique was considered difficult and therefore has only been adopted by a limited number of experienced operators.
Patients (n = 68) with a CTO of a native coronary artery treated by a single operator with this technique were included.
The right coronary artery was involved in 79.4%, the morphology was blunt in 77.9%, and CTO length was longer than 20 mm in 67.6%. Angiographic success rate was 80.9% with a 70.6% rate of complete recanalization. Stent implantation was performed in 82.3% of cases, with drug-eluting stents (DES) implanted in the majority (92.7%). Procedural complications occurred in 10.3% of cases. There were no episodes of myocardial infarction during follow-up, with 1 case (1.5%) of cardiac death. There were no cases of definite or probable stent thrombosis, and there was 1 (1.5%) possible stent thrombosis. The overall rate of in-segment binary restenosis was 44.7%, and target lesion revascularization (TLR) was performed in 25% of lesions. The rate of TLR in lesions treated with DES was 29.4% and in those treated with bare-metal stents was 50%.
The contrast-guided STAR technique appears to be feasible and relatively safe. However, this procedure is limited by a high rate of restenosis even with DES, and a second procedure may be necessary to obtain a definitive result.
评估使用造影剂引导的改良内膜下追踪及再入路(STAR)手术的操作及临床结果。
既往数据显示,采用STAR技术再通慢性完全闭塞病变(CTO)是可行的。然而,该技术被认为难度较大,因此仅被少数有经验的术者采用。
纳入由单一术者采用该技术治疗的68例冠状动脉CTO患者。
右冠状动脉病变占79.4%,病变形态钝圆者占77.9%,CTO长度超过20 mm者占$67.6%$。造影成功率为80.9%,完全再通率为70.6%。82.3%的病例进行了支架植入,其中大多数(92.7%)植入了药物洗脱支架(DES)。10.3%的病例发生了手术并发症。随访期间无心肌梗死事件发生,心脏死亡1例(1.5%)。无明确或可能的支架血栓形成病例,有1例(1.5%)可能的支架血栓形成。节段内二元再狭窄总发生率为44.7%,25%的病变进行了靶病变血运重建(TLR)。DES治疗病变的TLR率为29.4%,裸金属支架治疗病变的TLR率为50%。
造影剂引导的STAR技术似乎可行且相对安全。然而,即使使用DES,该手术仍受再狭窄率高的限制,可能需要二次手术才能获得确切结果。