Reyblat Polina, Chan Kevin G, Josephson David Y, Stein John P, Freeman John A, Grossfeld Gary D, Esrig David, Ginsberg David A
Department of Urology, Keck School of Medicine, University of Southern California, Rancho Los Amigos National Rehabilitation Center, Los Angeles, California, USA.
World J Urol. 2009 Feb;27(1):63-8. doi: 10.1007/s00345-008-0351-3. Epub 2008 Nov 20.
Augmentation enterocystoplasty is the standard treatment for patients with neurogenic bladder who have failed medical management. Our "extraperitoneal" approach involves a small peritoneotomy to obtain the segment of bowel for augmentation, and a standard "clam" enterocystoplasty. We compared operative and postoperative parameters and clinical outcomes of this technique with the standard intraperitoneal technique.
We retrospectively reviewed charts of 73 patients with neurogenic voiding dysfunction refractory to medical management who underwent augmentation enterocystoplasty alone or in conjunction with additional procedures. A total of 49 patients underwent extraperitoneal augmentation and 24 patients underwent intraperitoneal augmentation. Operative and postoperative parameters including time of surgery, estimated blood loss, need for blood transfusion, time for return of bowel function, and length of hospital stay were examined. Clinical outcomes including early and late postoperative complications, and continence status were also analyzed.
Median follow-up was 2.5 years. Patients in the extraperitoneal group had significantly shorter operative time (3.9 vs. 5.6 h, P < 0.0001); shorter hospital stay (8.0 vs. 10.5 days, P = 0.009); and shorter time to return of bowel function (3.5 vs. 4.9 days, P = 0.0005). There was no significant difference in complication rates. Postoperative continence was equally improved in both groups. When only patients with no prior abdominal surgery were compared, the findings were analogous: shorter operative time, shorter length of stay, sooner return of bowel function, and no difference in complication rate.
The extraperitoneal technique provides an equally effective method of bladder augmentation to the standard technique with easier early postoperative recovery.
扩大膀胱成形术是药物治疗失败的神经源性膀胱患者的标准治疗方法。我们的“腹膜外”方法包括一个小的腹膜切开术以获取用于扩大膀胱的肠段,以及标准的“夹闭”膀胱扩大术。我们将该技术与标准的腹膜内技术的手术及术后参数和临床结果进行了比较。
我们回顾性分析了73例药物治疗无效的神经源性排尿功能障碍患者的病历,这些患者单独或联合其他手术接受了扩大膀胱成形术。其中49例患者接受了腹膜外扩大膀胱成形术,24例患者接受了腹膜内扩大膀胱成形术。对手术及术后参数进行了检查,包括手术时间、估计失血量、输血需求、肠功能恢复时间和住院时间。还分析了临床结果,包括术后早期和晚期并发症以及控尿状态。
中位随访时间为2.5年。腹膜外组患者的手术时间明显更短(3.9 vs. 5.6小时,P < 0.0001);住院时间更短(8.0 vs. 10.5天,P = 0.009);肠功能恢复时间更短(3.5 vs. 4.9天,P = 0.0005)。并发症发生率无显著差异。两组术后控尿情况均有同等改善。当仅比较无腹部手术史的患者时,结果类似:手术时间更短、住院时间更短、肠功能恢复更快,且并发症发生率无差异。
腹膜外技术为膀胱扩大提供了一种与标准技术同样有效的方法,且术后早期恢复更容易。