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不明原因不孕夫妇何时选择寻求医疗帮助?

When do involuntarily infertile couples choose to seek medical help?

机构信息

Inserm, Institut National de la Santé et de la Recherche Médicale, Unit 822, Epidemiology, Demography, and Social Sciences, Le Kremlin-Bicêtre, France.

出版信息

Fertil Steril. 2010 Feb;93(3):737-44. doi: 10.1016/j.fertnstert.2008.10.011. Epub 2008 Nov 19.

Abstract

OBJECTIVE

To estimate the probability of medical consultation for infertility during the course of a pregnancy attempt and to study its determinants.

DESIGN

Pregnancy-based retrospective telephone survey analyzed with a discrete time Cox model.

SETTING

Two rural counties in Brittany and Normandy, France.

PATIENT(S): A random sample of 901 women from the general population aged 18-60 years reporting 1,460 pregnancy attempts resulting in a live birth between 1985 and 2000 (participation rate, 73%).

INTERVENTION(S): None.

MAIN OUTCOME MEASURE(S): Probability of medical consultation for involuntary infertility cumulated over time.

RESULT(S): The cumulative probability of medical consultation for involuntary infertility among nulligravid women was 45% after 12 months of involuntary infertility and 75% after 24 months. The probability of medical consultation at any time was half that for parous women (odds ratio 0.4, 95% confidence interval 0.2-0.6). More highly educated women were more likely to have sought medical help for infertility. Only 45% of women who had sought medical advice received infertility treatment.

CONCLUSION(S): Our survival approach provides a description of infertility service use during the course of a pregnancy attempt, and confirms that parity and educational level are strong predictors of medical help-seeking behaviors.

摘要

目的

评估在妊娠尝试过程中因不孕而寻求医疗咨询的概率,并研究其决定因素。

设计

基于妊娠的回顾性电话调查,采用离散时间 Cox 模型进行分析。

地点

法国布列塔尼和诺曼底的两个农村县。

患者

1985 年至 2000 年间,年龄在 18-60 岁之间的普通人群中随机抽取的 901 名报告了 1460 次妊娠尝试并导致活产的女性(参与率为 73%)。

干预措施

无。

主要观察指标

随时间推移累积的因非意愿性不孕而寻求医疗咨询的概率。

结果

在 12 个月的非意愿性不孕后,初产妇中因非意愿性不孕而寻求医疗咨询的累积概率为 45%,在 24 个月后为 75%。与经产妇相比,任何时候寻求医疗帮助的可能性都减半(优势比 0.4,95%置信区间 0.2-0.6)。受教育程度较高的女性更有可能因不孕寻求医疗帮助。只有 45%寻求过医疗咨询的女性接受了不孕治疗。

结论

我们的生存方法提供了对妊娠尝试过程中不孕服务利用的描述,并证实了经产和教育水平是寻求医疗帮助行为的强有力预测因素。

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