Madan V, Hindle E, Hussain W, August P J
Laser Division, The Dermatology Centre, Salford Royal Hospital NHS Foundation Trust, Stott Lane, Salford, Manchester M6 8HD, UK.
Br J Dermatol. 2008 Dec;159(6):1309-14. doi: 10.1111/j.1365-2133.2008.08932.x.
Hidradenitis suppurativa (HS) is a chronic and often a recalcitrant inflammatory skin condition.
To present the results of carbon dioxide (CO2) laser treatment of recalcitrant HS in nine patients who had failed to improve on medical and other surgical treatments.
HS lesions consisting of abscesses, sinuses and granulation tissue were completely excised using the cutting mode of a CO2 laser, leaving only healthy residual subcutaneous fat. The wounds were closed by primary intention where possible and left to granulate otherwise. Outcomes were determined by clinical review and questionnaire.
Twenty-seven sites were treated in 19 sessions on nine patients. Seven procedures were performed under general anaesthesia and 12 under local. All patients rated their postoperative discomfort as less or equal to their preoperative state. Seven of the nine patients had complete remission for 12 months or longer after their last laser treatment and ceased all medications. High levels of patient satisfaction were reported with CO2 laser treatment. The main complication was axillary scar contracture in two patients but this was insufficient to limit limb movement.
CO2 laser treatment should be considered as a treatment option in recalcitrant HS, where multiple medical treatments have been ineffective.
化脓性汗腺炎(HS)是一种慢性且通常难以治愈的炎症性皮肤病。
介绍二氧化碳(CO2)激光治疗9例经药物及其他手术治疗无效的顽固性HS患者的结果。
使用CO2激光的切割模式将由脓肿、窦道和肉芽组织组成的HS病变完全切除,仅保留健康的残余皮下脂肪。伤口尽可能一期缝合,否则任其肉芽生长。通过临床检查和问卷调查确定结果。
9例患者共进行了19次治疗,治疗27个部位。7例手术在全身麻醉下进行,12例在局部麻醉下进行。所有患者术后不适程度均小于或等于术前。9例患者中有7例在最后一次激光治疗后完全缓解12个月或更长时间,且停用了所有药物。患者对CO2激光治疗的满意度较高。主要并发症是2例患者出现腋窝瘢痕挛缩,但这并不足以限制肢体活动。
对于多种药物治疗无效的顽固性HS,应考虑将CO2激光治疗作为一种治疗选择。