Patel J R, Heldens J G M
JAS Biologicals Limited, The Centre for Veterinary Science, Madingley Road, Cambridge CB3OES, UK.
Vaccine. 2009 Jan 22;27(4):491-504. doi: 10.1016/j.vaccine.2008.11.027. Epub 2008 Nov 27.
In this article we review important established, newly emergent and potential viral diseases of cats, dogs and rabbits. Topics covered include virus epidemiology, disease pathogenesis, existing and prospective immunoprophylaxis against the viruses. For some feline viruses, notably the immunodeficiency virus, leukaemia virus and peritonitis virus, available vaccines are poorly efficacious but there are good prospects for this. A further challenge for the industry is likely to be due to viruses jumping species and the emergence of more virulent variants of established viruses resulting from mutations as has been the case for the canine parvovirus, coronaviruses and feline calicivirus.
在本文中,我们回顾了猫、狗和兔子重要的已确定、新出现和潜在的病毒性疾病。涵盖的主题包括病毒流行病学、疾病发病机制、针对这些病毒的现有和前瞻性免疫预防措施。对于一些猫病毒,尤其是免疫缺陷病毒、白血病病毒和腹膜炎病毒,现有的疫苗效果不佳,但对此有良好的前景。该行业面临的另一个挑战可能是由于病毒跨物种传播以及现有病毒因突变产生更具毒性的变种,犬细小病毒、冠状病毒和猫杯状病毒就是这种情况。