相似文献
1
Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease.
Semin Cell Dev Biol. 2009 Apr;20(2):191-200. doi: 10.1016/j.semcdb.2008.10.005. Epub 2008 Oct 17.
2
Functional role of lipoprotein receptors in Alzheimer's disease.
Curr Alzheimer Res. 2008 Feb;5(1):15-25. doi: 10.2174/156720508783884675.
3
Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.
Mol Neurodegener. 2006 Aug 18;1:8. doi: 10.1186/1750-1326-1-8.
4
GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.
Mol Biol Cell. 2012 Jul;23(14):2645-57. doi: 10.1091/mbc.E12-01-0014. Epub 2012 May 23.
5
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
J Biol Chem. 2004 Jul 9;279(28):29639-46. doi: 10.1074/jbc.M313893200. Epub 2004 May 4.
6
Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes.
J Biol Chem. 2018 Jul 20;293(29):11341-11357. doi: 10.1074/jbc.RA117.000441. Epub 2018 Jun 1.
7
The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.
J Neurosci. 2006 Feb 1;26(5):1596-603. doi: 10.1523/JNEUROSCI.4946-05.2006.
8
LRP in amyloid-beta production and metabolism.
Ann N Y Acad Sci. 2006 Nov;1086:35-53. doi: 10.1196/annals.1377.005.
9
LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease.
Mol Neurodegener. 2012 Jun 26;7:31. doi: 10.1186/1750-1326-7-31.
10
α(2A) adrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction.
Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17296-301. doi: 10.1073/pnas.1409513111. Epub 2014 Nov 17.
引用本文的文献
1
Polyunsaturated fatty acids in lipid membranes regulate human neuronal function and amyloid-β production.
iScience. 2025 May 12;28(6):112557. doi: 10.1016/j.isci.2025.112557. eCollection 2025 Jun 20.
2
Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cognitive impairment in patients with acute mild ischemic stroke.
Eur J Med Res. 2025 May 30;30(1):430. doi: 10.1186/s40001-025-02693-2.
3
The Intersection of cerebral cholesterol metabolism and Alzheimer's disease: Mechanisms and therapeutic prospects.
Heliyon. 2024 Apr 30;10(9):e30523. doi: 10.1016/j.heliyon.2024.e30523. eCollection 2024 May 15.
4
Utilizing Proteomic Approaches to Uncover the Neuroprotective Effects of ACE Inhibitors: Implications for Alzheimer's Disease Treatment.
Molecules. 2023 Aug 8;28(16):5938. doi: 10.3390/molecules28165938.
5
LRP1B suppresses HCC progression through the NCSTN/PI3K/AKT signaling axis and affects doxorubicin resistance.
Genes Dis. 2022 Nov 23;10(5):2082-2096. doi: 10.1016/j.gendis.2022.10.021. eCollection 2023 Sep.
6
Alzheimer's disease is an inherent, natural part of human brain aging: an integrated perspective.
Free Neuropathol. 2022 Jul 8;3:17. doi: 10.17879/freeneuropathology-2022-3806. eCollection 2022 Jan.
7
The Multifaceted Role of WNT Signaling in Alzheimer's Disease Onset and Age-Related Progression.
Cells. 2023 Apr 21;12(8):1204. doi: 10.3390/cells12081204.
8
Lipid Peroxidation Induced ApoE Receptor-Ligand Disruption as a Unifying Hypothesis Underlying Sporadic Alzheimer's Disease in Humans.
J Alzheimers Dis. 2022;87(3):1251-1290. doi: 10.3233/JAD-220071.
9
Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise.
FEBS J. 2023 Mar;290(6):1420-1453. doi: 10.1111/febs.16344. Epub 2022 Jan 18.
10
The apolipoprotein receptor LRP3 compromises APP levels.
Alzheimers Res Ther. 2021 Nov 2;13(1):181. doi: 10.1186/s13195-021-00921-5.
本文引用的文献
1
The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics-relevance for Alzheimer's disease.
Prog Neurobiol. 2008 Aug;85(4):393-406. doi: 10.1016/j.pneurobio.2008.05.002. Epub 2008 Jul 7.
2
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
Nat Med. 2008 Aug;14(8):837-42. doi: 10.1038/nm1782. Epub 2008 Jun 22.
3
Regulated proteolysis of APP and ApoE receptors.
Mol Neurobiol. 2008 Feb;37(1):64-72. doi: 10.1007/s12035-008-8017-0. Epub 2008 Apr 15.
4
Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein.
Mol Neurodegener. 2008 Mar 18;3:5. doi: 10.1186/1750-1326-3-5.
5
Independent inhibition of Alzheimer disease beta- and gamma-secretase cleavage by lowered cholesterol levels.
J Biol Chem. 2008 Apr 25;283(17):11302-11. doi: 10.1074/jbc.M801520200. Epub 2008 Feb 28.
6
Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.
J Biol Chem. 2008 Apr 25;283(17):11501-8. doi: 10.1074/jbc.M800642200. Epub 2008 Feb 13.
7
Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.
J Neurochem. 2008 May;105(4):1536-49. doi: 10.1111/j.1471-4159.2008.05283.x. Epub 2008 Feb 5.
8
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.
J Clin Invest. 2008 Feb;118(2):671-82. doi: 10.1172/JCI33622.
9
A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference.
J Neurosci. 2007 Dec 26;27(52):14459-69. doi: 10.1523/JNEUROSCI.4701-07.2007.
10
Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production.
Neurobiol Dis. 2008 Mar;29(3):422-37. doi: 10.1016/j.nbd.2007.10.005. Epub 2007 Nov 4.
Zotero 插件