索拉非尼治疗成人横纹肌样肾细胞癌
Treatment of adult rhabdoid renal cell carcinoma with sorafenib.
作者信息
Kapoor Anil, Tutino Robert, Kanaroglou Androniki, Hotte Sebastien J
机构信息
Division of Urology, Department of Surgery, McMaster University, Hamilton, Ont., and the.
出版信息
Can Urol Assoc J. 2008 Dec;2(6):631-4. doi: 10.5489/cuaj.983.
Abstract
Renal cell carcinoma (RCC) with rhabdoid features is an uncommon and highly aggressive malignancy. We report a case of adult clear-cell RCC with extensive rhabdoid features treated with the tyrosine kinase inhibitor sorafenib. A review of the literature summarizes important aspects of this malignancy. We discuss clinical and histological findings as well as the patient's response to sorafenib therapy.
摘要
具有横纹肌样特征的肾细胞癌（RCC）是一种罕见且侵袭性很强的恶性肿瘤。我们报告了一例采用酪氨酸激酶抑制剂索拉非尼治疗的具有广泛横纹肌样特征的成人透明细胞肾细胞癌病例。文献回顾总结了这种恶性肿瘤的重要方面。我们讨论了临床和组织学发现以及患者对索拉非尼治疗的反应。
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