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[皮肤真菌病——分类、病因、发病机制及治疗]

[Dermatomycosis--classification, etiology, pathogenesis, and treatment].

作者信息

Watanabe Shinichi

机构信息

Department of Dermatology, Teikyo University School of Medicine.

出版信息

Nihon Rinsho. 2008 Dec;66(12):2285-9.

Abstract

Dermatomycoses are common diseases in dermatological clinics. An epidemiological survey in Japan revealed that dermatophytosis was the most prevalent cutaneous fungal infection (89.1%), followed by candidiasis (8.4%) and the Malassezia infections(2.4%). Among dermatophytoses, tinea pedis was the most frequent, then in decreasing order, tinea unguium, tinea corporis, tinea cruris, tinea manuum, and tinea capitis including kerion. Among all dermatophyte infections, Trichophyton rubrum was the most frequently isolated. Among cutaneous candidiasis, intertrigo was the most frequent clinical form, followed by erosio interdigitalis and diaper candidiasis. Dermatomycoses may provoke several inflammatory reactions, but the organisms causing them are located in the keratin layer of the epidermis. Therefore, topical application is the first line therapy for the most dermatomycoses.

摘要

皮肤真菌病是皮肤科门诊的常见疾病。日本的一项流行病学调查显示,皮肤癣菌病是最常见的皮肤真菌感染(89.1%),其次是念珠菌病(8.4%)和马拉色菌感染(2.4%)。在皮肤癣菌病中,足癣最为常见,其次依次为甲癣、体癣、股癣、手癣和头癣(包括脓癣)。在所有皮肤癣菌感染中,红色毛癣菌是最常分离出的菌种。在皮肤念珠菌病中,擦烂是最常见的临床类型,其次是指间糜烂和尿布念珠菌病。皮肤真菌病可能引发多种炎症反应,但引起这些疾病的病原体位于表皮角质层。因此,局部用药是大多数皮肤真菌病的一线治疗方法。

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