Hazarika Pompi, Jickells Sue M, Russell David A
School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich, Norfolk, UKNR4 7TJ.
Analyst. 2009 Jan;134(1):93-6. doi: 10.1039/b816273e. Epub 2008 Nov 25.
Magnetic particles functionalised with anti-cotinine antibody have been used to image latent fingermarks through the detection of the cotinine antigen in the sweat deposited within the fingerprints of smokers. The antibody-magnetic particle conjugates are readily applied to latent fingerprints while excess reagents are removed through the use of a magnetic wand. The results have shown that drug metabolites, such as cotinine, can be detected and used to image the fingermark to establish the identity of an individual within 15 minutes.
用抗可替宁抗体功能化的磁性颗粒已被用于通过检测吸烟者指纹内汗液中的可替宁抗原对潜在指纹进行成像。抗体 - 磁性颗粒偶联物很容易应用于潜在指纹,同时通过使用磁棒去除多余的试剂。结果表明,药物代谢物,如可替宁,可以在15分钟内被检测到,并用于对指纹进行成像以确定个人身份。