Transcription. Gene expression--where to start?
作者信息
Buratowski Stephen
机构信息
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
出版信息
Science. 2008 Dec 19;322(5909):1804-5. doi: 10.1126/science.1168805.
Abstract
摘要
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本文引用的文献
1
Genome-wide structure and organization of eukaryotic pre-initiation complexes.真核生物起始前复合物的全基因组结构和组织。
Nature. 2012 Jan 18;483(7389):295-301. doi: 10.1038/nature10799.
2
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution.在单核苷酸分辨率下检测到全基因组范围内的蛋白质-DNA 相互作用。
Cell. 2011 Dec 9;147(6):1408-19. doi: 10.1016/j.cell.2011.11.013.
3
Uniform transitions of the general RNA polymerase II transcription complex.通用 RNA 聚合酶 II 转录复合物的一致转变。
Nat Struct Mol Biol. 2010 Oct;17(10):1272-8. doi: 10.1038/nsmb.1903. Epub 2010 Sep 5.
4
Widespread bidirectional promoters are the major source of cryptic transcripts in yeast.广泛存在的双向启动子是酵母中隐秘转录本的主要来源。
Nature. 2009 Feb 19;457(7232):1038-42. doi: 10.1038/nature07747. Epub 2009 Jan 25.
5
Bidirectional promoters generate pervasive transcription in yeast.双向启动子在酵母中产生广泛的转录。
Nature. 2009 Feb 19;457(7232):1033-7. doi: 10.1038/nature07728. Epub 2009 Jan 25.
6
A transcription-independent role for TFIIB in gene looping.TFIIB在基因环化中不依赖转录的作用。
Mol Cell. 2007 Sep 7;27(5):806-16. doi: 10.1016/j.molcel.2007.07.013.
7
Identification and distinct regulation of yeast TATA box-containing genes.酵母中含TATA框基因的鉴定与差异调控。
Cell. 2004 Mar 5;116(5):699-709. doi: 10.1016/s0092-8674(04)00205-3.
8
A genome-wide housekeeping role for TFIID and a highly regulated stress-related role for SAGA in Saccharomyces cerevisiae.在酿酒酵母中，TFIID具有全基因组范围的管家功能，而SAGA在应激相关方面具有高度调控的功能。
Mol Cell. 2004 Feb 27;13(4):573-85. doi: 10.1016/s1097-2765(04)00087-5.
9
A histone fold TAF octamer within the yeast TFIID transcriptional coactivator.酵母TFIID转录共激活因子中的一个组蛋白折叠TAF八聚体。
Nat Struct Biol. 2001 Aug;8(8):695-700. doi: 10.1038/90408.
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Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II.TAFs与核心元件的结合通过RNA聚合酶II指导启动子选择性。
Cell. 1995 Jun 30;81(7):1115-25. doi: 10.1016/s0092-8674(05)80016-9.
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