促甲状腺激素和环磷酸腺苷对在化学成分明确的培养基中培养的人甲状腺细胞的影响。
Effects of TSH and cyclic AMP on the human thyroid cells cultured in a chemically defined medium.
作者信息
Kaneko Y
出版信息
Experientia. 1977 Feb 15;33(2):281-2. doi: 10.1007/BF02124113.
PMID:191290
Abstract
In a serum-free, chemically defined medium human thyroid cells elongated remarkably and resembled fibroblastic cells. They retained the cyclic AMP response to TSH and the supplement of medium with TSH or dibutyryl cyclic AMP permitted the preservation of epithelial nature by the cells. Cyclic AMP of the cells of epithelial nature was higher than those of fibroblastic appearance.
摘要
在无血清、化学成分明确的培养基中，人甲状腺细胞显著伸长，类似成纤维细胞。它们保留了对促甲状腺激素（TSH）的环磷酸腺苷（cAMP）反应，用TSH或二丁酰环磷酸腺苷补充培养基可使细胞保持上皮性质。具有上皮性质的细胞的环磷酸腺苷水平高于成纤维细胞形态的细胞。
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