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肯尼亚马库埃尼区当地种植玉米中的黄曲霉毒素含量。

Aflatoxin levels in locally grown maize from Makueni District, Kenya.

作者信息

Mwihia J T, Straetmans M, Ibrahim A, Njau J, Muhenje O, Guracha A, Gikundi S, Mutonga D, Tetteh C, Likimani S, Breiman R F, Njenga K, Lewis L

机构信息

National Public Health Laboratory Services, Kenya, P.O. Box 20750-00202, Nairobi, Kenya.

出版信息

East Afr Med J. 2008 Jul;85(7):311-7. doi: 10.4314/eamj.v85i7.9648.

Abstract

OBJECTIVES

Investigations were carried out to determine aflatoxin levels in household maize in Makueni District and to correlate aflatoxin levels to maize drying and storage practices. Also, aflatoxin exposure in villages that reported aflatoxicosis cases in 2005 was compared with that in villages that did not report cases to assess whether aflatoxin exposure levels could be used to identify high-risk villages for targeted prevention interventions.

DESIGN

A cross-sectional study.

SETTING

Three divisions of Makueni district, Kibwezi, Makindu and Mtito Andei in Eastern Province, Kenya.

SUBJECTS

Ninety six households were surveyed, and 104 maize samples were analysed for total aflatoxin levels from June to July 2005. The households were selected from high and low aflatoxicosis risk areas.

RESULTS

Out of the 104 maize samples collected from 96 households, 37 (35.5%) had aflatoxin levels above the World Health Organisation (WHO) recommended maximum limit of 20 ppb. All of these samples were homegrown or purchased. Twenty one samples (20.1%) had levels above 100 ppb. Eleven (10.6%) had extremely high levels above 1000 ppb. No relief supply maize had aflatoxin levels above the WHO maximum limit.

CONCLUSION

High levels of aflatoxin in homegrown and purchased maize suggested that aflatoxin exposure was widespread.

摘要

目的

开展调查以确定马库埃尼区家庭玉米中的黄曲霉毒素水平,并将黄曲霉毒素水平与玉米干燥和储存方式相关联。此外,还比较了2005年报告有黄曲霉毒素中毒病例的村庄与未报告病例的村庄中的黄曲霉毒素暴露情况,以评估黄曲霉毒素暴露水平是否可用于识别需要进行针对性预防干预的高风险村庄。

设计

横断面研究。

地点

肯尼亚东部省马库埃尼区的三个分区,即基布韦齐、马金杜和姆蒂托安代伊。

研究对象

对96户家庭进行了调查,并于2005年6月至7月分析了104份玉米样品中的总黄曲霉毒素水平。这些家庭选自黄曲霉毒素中毒高风险和低风险地区。

结果

从96户家庭收集的104份玉米样品中,37份(35.5%)的黄曲霉毒素水平高于世界卫生组织(WHO)建议的20 ppb的最大限量。所有这些样品均为自家种植或购买所得。21份样品(20.1%)的黄曲霉毒素水平高于100 ppb。11份(10.6%)的黄曲霉毒素水平极高,高于1000 ppb。救济供应的玉米中没有黄曲霉毒素水平高于WHO最大限量的情况。

结论

自家种植和购买的玉米中黄曲霉毒素水平较高,表明黄曲霉毒素暴露情况普遍。

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