Chung Frances, Yuan Hongbo, Yin Ling, Vairavanathan Santhira, Wong David T
Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Anesth Analg. 2009 Feb;108(2):467-75. doi: 10.1213/ane.0b013e318176bc19.
Preoperative testing has been criticized as having little impact on perioperative outcomes. We conducted a randomized, single-blind, prospective, controlled pilot study to determine whether indicated preoperative testing can be eliminated without increasing the perioperative incidence of adverse events in selected patients undergoing ambulatory surgery.
One thousand sixty-one eligible patients were randomized either to have indicated preoperative testing or no preoperative testing. In the indicated testing group, patients received indicated preoperative testing: a complete blood count, electrolytes, blood glucose, creatinine, electrocardiogram, and chest radiograph according to the Ontario Preoperative Testing Grid as per current practice, whereas in the no testing group, no testing was ordered. The investigators, data collectors, and patient outcome reviewers were blinded to the group assignment. The primary outcome measures were the rate of perioperative adverse events and the rates of adverse events within 7 and 30 days after surgery.
Patients' age, gender, American Society of Anesthesiologists status, type of surgery, and anesthesia were similar between the two groups. There were no significant differences in the rates of perioperative adverse events and the rates of adverse events within 30 days after surgery between the no testing group and the indicated testing group. Hospital revisits <or=7 days were higher in the indicated testing group (P < 0.05). None of the adverse events were related to the indicated testing or no testing.
This pilot study showed that there was no increase in the perioperative adverse events as a result of no preoperative testing in our study population. A larger study is needed to demonstrate that indicated testing may be safely eliminated in selected patients undergoing ambulatory surgery without increasing perioperative complications.
术前检查一直受到批评,因其对围手术期结局影响甚微。我们开展了一项随机、单盲、前瞻性对照试验性研究,以确定在接受门诊手术的特定患者中,是否可以取消必要的术前检查而不增加围手术期不良事件的发生率。
1061例符合条件的患者被随机分为接受必要术前检查组或不接受术前检查组。在必要检查组中,患者按照安大略省术前检查标准流程接受必要的术前检查:全血细胞计数、电解质、血糖、肌酐、心电图和胸部X线检查;而在不检查组中,不安排任何检查。研究人员、数据收集者和患者结局评估者对分组情况不知情。主要结局指标为围手术期不良事件发生率以及术后7天和30天内的不良事件发生率。
两组患者的年龄、性别、美国麻醉医师协会分级、手术类型和麻醉方式相似。不检查组和必要检查组在围手术期不良事件发生率以及术后30天内的不良事件发生率方面无显著差异。必要检查组术后7天内再次入院率较高(P<0.05)。所有不良事件均与是否进行必要检查无关。
这项试验性研究表明,在我们的研究人群中,不进行术前检查并未增加围手术期不良事件的发生率。需要开展更大规模的研究来证明,在接受门诊手术的特定患者中,可以安全地取消必要检查而不增加围手术期并发症。