Mbanya Dora, Sama Martyn, Tchounwou Paul
Faculty of Medicine & Biomedical Sciences, University of Yaoundé I, Cameroon.
Int J Environ Res Public Health. 2008 Dec;5(5):378-83. doi: 10.3390/ijerph5050378.
Nearly three decades after its discovery, HIV infection remains the number one killer disease in Sub- Saharan Africa where up to 67% of the world's 33 million infected people live. In Cameroon, based on a Demographic Health Survey carried out in 2004, the national HIV prevalence is estimated at 5.5% with women and youths being predominantly infected. Orphans and vulnerable children (OVC) from the HIV and AIDS pandemic have increased steadily over the years; hospital occupancy is estimated at about 30%, hence stretching the health system; co-infections like HIV/tuberculosis have been reported to reach 40-50% of infected cases and 95% of teachers are said not to be productive on several counts. Thus, the impact is multi-sectorial. Furthermore, the HIV epidemic in Cameroon is peculiar because of the wide HIV-1 genetic diversity of HIV-1 Group M observed with several subtypes reported (A, B, C, D, F, G, H, J, K), predominantly subtype A. There are also circulating recombinant forms, mainly CRF02_AG. In addition, HIV-1 Groups O and N have all been noted in Cameroon. These findings have great implications not only for HIV diagnosis, but also for responsiveness to therapy as well as for vaccine development. In 1986, the initial response of the Cameroon government to the increasing trends in the HIV/AIDS infection was to create a National AIDS Control Committee to coordinate a national AIDS programme. By 2000, the first National Strategic Plan was drawn for 2000-2005. The second National Strategic Plan for 2006-2010 is currently being implemented and covers various axes. Some results obtained show that there has been significantly positive outcomes noted in the various arms of intervention by the Cameroon government.
在发现艾滋病毒感染近三十年之后,它仍是撒哈拉以南非洲的头号致命疾病,全球3300万感染者中有多达67%生活在该地区。在喀麦隆,根据2004年进行的人口健康调查,全国艾滋病毒感染率估计为5.5%,主要感染人群为妇女和青年。多年来,因艾滋病毒/艾滋病大流行产生的孤儿和弱势儿童数量稳步增加;医院床位占用率估计约为30%,从而使卫生系统不堪重负;据报道,艾滋病毒/结核病等合并感染病例占感染病例的40%-50%,并且据说95%的教师在多个方面效率低下。因此,其影响是多部门的。此外,喀麦隆的艾滋病毒流行情况很特殊,因为观察到艾滋病毒-1 M组存在广泛的艾滋病毒-1基因多样性,报告了几种亚型(A、B、C、D、F、G、H、J、K),主要是A型。也存在循环重组型,主要是CRF02_AG。此外,在喀麦隆还发现了艾滋病毒-1 O组和N组。这些发现不仅对艾滋病毒诊断有重大影响,而且对治疗反应以及疫苗开发也有重大影响。1986年,喀麦隆政府对艾滋病毒/艾滋病感染增加趋势的初步反应是设立了国家艾滋病控制委员会,以协调国家艾滋病防治计划。到2000年,制定了2000-2005年第一个国家战略计划。目前正在实施2006-2010年第二个国家战略计划,该计划涵盖多个方面。所取得的一些结果表明,喀麦隆政府在各个干预领域都取得了显著的积极成果。