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撤回:糖尿病患者的常规监测系统。

WITHDRAWN: Systems for routine surveillance in people with diabetes mellitus.

作者信息

Griffin Simon J, Kinmonth Ann-Louise

机构信息

MRC Epidemiology Unit, Institute of Metabolic Science, Box 285, Addenbrooke's Hospital, Hills Road, Cambridge, UK, CB2 0QQ.

出版信息

Cochrane Database Syst Rev. 2009 Jan 21;2009(1):CD000541. doi: 10.1002/14651858.CD000541.pub2.

Abstract

BACKGROUND

There is wide variation in the extent of general practice involvement in diabetes care.

OBJECTIVES

To assess the effects of involving primary care professionals in the routine review and surveillance for complications of people with established diabetes mellitus compared with secondary care specialist follow up.

SEARCH STRATEGY

We searched the Cochrane Diabetes Group specialised register, The Cochrane Library, MEDLINE (January 1966 to December 1996), EMBASE (to December 1996), Cinahl (to December 1996), National Research Register (to December 1996), PsycLIT (to December 1996), HealthSTAR (to December 1996), CRIB (to December 1996), Dissertation Abstracts (to December 1996), and reference lists of articles.

SELECTION CRITERIA

Randomised trials in which people with diabetes were allocated to a system of review and surveillance for complications by primary care professionals. Outcomes included mortality, metabolic control, cardiovascular risk factors, quality of life, functional status, satisfaction, hospital admissions, costs, completeness of screening, and development of complications.

DATA COLLECTION AND ANALYSIS

The reviewer assessed trial quality and extracted data. Analysis was on an intention to treat basis. General practice care was categorised into routine or prompted care and a stratified analysis undertaken.

MAIN RESULTS

Five trials involving 1058 people were included. Results were heterogeneous between trials. In those schemes featuring more intensive support through a prompting system for general practitioners and patients, there was no difference in mortality between hospital and general practice care (odds ratio 1.06, 95% confidence interval 0.53 to 2.11), HbA1 tended to be lower (a weighted difference in means of -0.27%, 95% confidence interval -0.59 to 0.03) and losses to follow up were significantly lower (odds ratio 0.37, 95% confidence interval 0.22 to 0.61) in primary care. However, schemes with less well-developed support for family doctors were associated with adverse outcomes for patients. Quality of life, cardiovascular risk factors, functional status and the development of complications were infrequently assessed.

AUTHORS' CONCLUSIONS: Unstructured care in the community is associated with poorer follow up, greater mortality and worse glycaemic control than hospital care. Computerised central recall, with prompting for patients and their family doctors, can achieve standards of care as good or better than hospital outpatient care, at least in the short term. The evidence supports provision of regular prompted recall and review of people with diabetes by willing general practitioners and demonstrates that this can be achieved, if suitable organisation is in place.

摘要

背景

普通科在糖尿病护理中的参与程度差异很大。

目的

评估与二级医疗专科随访相比,让初级保健专业人员参与对已确诊糖尿病患者并发症的常规复查和监测的效果。

检索策略

我们检索了Cochrane糖尿病小组专门注册库、Cochrane图书馆、MEDLINE(1966年1月至1996年12月)、EMBASE(至1996年12月)、Cinahl(至1996年12月)、国家研究注册库(至1996年12月)、PsycLIT(至1996年12月)、HealthSTAR(至1996年12月)、CRIB(至1996年12月)、学位论文摘要(至1996年12月)以及文章的参考文献列表。

入选标准

随机试验,其中糖尿病患者被分配到由初级保健专业人员进行并发症复查和监测的系统。结局包括死亡率、代谢控制、心血管危险因素、生活质量、功能状态、满意度、住院次数、费用、筛查完整性以及并发症的发生情况。

数据收集与分析

评审员评估试验质量并提取数据。分析基于意向性分析。普通科护理分为常规护理或提示性护理,并进行分层分析。

主要结果

纳入了5项涉及1058人的试验。试验结果存在异质性。在那些通过针对全科医生和患者的提示系统提供更强化支持的方案中,医院护理和普通科护理在死亡率方面没有差异(优势比1.06,95%置信区间0.53至2.11),初级保健中糖化血红蛋白(HbA1)倾向于更低(加权均值差异为-0.27%,95%置信区间-0.59至0.03),失访率显著更低(优势比0.37,95%置信区间0.22至0.61)。然而,对家庭医生支持不完善的方案与患者的不良结局相关。生活质量、心血管危险因素、功能状态以及并发症的发生情况很少被评估。

作者结论

与医院护理相比,社区的非结构化护理与随访较差、死亡率更高以及血糖控制更差相关。计算机化的集中召回,并向患者及其家庭医生提供提示,至少在短期内可以达到与医院门诊护理相当或更好的护理标准。证据支持由愿意参与的全科医生对糖尿病患者进行定期提示性召回和复查,并表明如果有合适的组织安排,这是可以实现的。

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