新生儿重症监护病房中镇静和镇痛的首选药物。
Drugs of choice for sedation and analgesia in the neonatal ICU.
作者信息
Hall R Whit, Shbarou Rolla M
机构信息
Division of Neonatology, University of Arkansas for Medical Sciences, Slot 512B, 4301 W Markham, Little Rock, AR 72205, USA.
出版信息
Clin Perinatol. 2009 Mar;36(1):15-26. doi: 10.1016/j.clp.2008.09.007.
Abstract
Painful procedures in the neonatal ICU are common, undertreated, and lead to adverse consequences. The drugs most commonly used to treat neonatal pain include the opiates, benzodiazepines, barbiturates, ketamine, propofol, acetaminophen, and local and topical anesthetics. This article discusses the indications for and advantages and disadvantages of the commonly used analgesic drugs. Guidance and references for drugs and dosing for specific neonatal procedures are provided.
摘要
新生儿重症监护病房（NICU）中的疼痛性操作很常见，治疗不足，并会导致不良后果。最常用于治疗新生儿疼痛的药物包括阿片类药物、苯二氮䓬类药物、巴比妥类药物、氯胺酮、丙泊酚、对乙酰氨基酚以及局部和外用麻醉剂。本文讨论了常用镇痛药物的适应证、优缺点。还提供了针对特定新生儿操作的药物及剂量的指导和参考文献。
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