Brace Christopher L
University of Wisconsin, Madison, WI 53792, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:230-3. doi: 10.1109/IEMBS.2008.4649132.
The development of microwave tumor ablation devices depends largely on numerical simulations of antenna characteristics and transient electromagnetic heating. However, without an adequate tissue model simulation predictions can vary widely from experimental results. In this study, tissue dielectric properties are measured to capture changes induced by temperature, cellular makeup and water content during thermal ablation. Measurements made using this technique agree closely with previous measurements for temperatures up to 50 degrees C, but both relative permittivity and conductivity decrease by as much as 50 percent when temperatures approach 100 degrees C.
微波肿瘤消融设备的发展在很大程度上依赖于天线特性和瞬态电磁加热的数值模拟。然而,如果没有合适的组织模型,模拟预测结果可能与实验结果有很大差异。在本研究中,测量了组织介电特性,以捕捉热消融过程中由温度、细胞组成和含水量引起的变化。使用该技术进行的测量与之前对高达50摄氏度温度的测量结果非常吻合,但当温度接近100摄氏度时,相对介电常数和电导率都会下降多达50%。