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《特怀奥罗娜地区毛利人的未诊断糖尿病、糖耐量受损和空腹血糖受损患病率:糖尿病预防策略》

Prevalence of undiagnosed diabetes, impaired glucose tolerance, and impaired fasting glucose among Maori in Te Wai o Rona: Diabetes Prevention Strategy.

作者信息

Simmons David, Rush Elaine, Crook Nic

机构信息

Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

出版信息

N Z Med J. 2009 Jan 23;122(1288):30-8.

Abstract

AIMS

To describe the prevalence of undiagnosed diabetes, impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) ("dysglycaemia") among Maori.

METHODS

Te Wai o Rona: Diabetes Prevention Strategy was a trial of lifestyle change among Maori families in the Waikato/Lakes areas of New Zealand. All Maori family household members aged > or = 28 years, without known diabetes, were invited to participate through primary care, community, and media approaches. Participants were invited to have an oral glucose tolerance test (OGTT).

RESULTS

Of the 3817 eligible Maori, mean BMI was 32.9+/-7.8 kg/m2 (women) and 33.1+/-6.7 kg/m2 (men). The age standardised prevalence of undiagnosed diabetes was higher among men than women (6.5[5.8-7.4]% vs 4.2[3.6-4.8]%), as was that for IFG (5.4[4.7-6.1]% vs 3.0[2.3-3.5]%), but not IGT (8.5[7.6-9.4]% vs 9.7[8.7-10.6]%) with no rural-urban differences. The prevalence of dysglycaemia increased with increasing BMI with no clear inflection point and was 1.33(1.11-1.60) greater among those with a community services card after adjusting for age, sex and BMI.

CONCLUSIONS

Undiagnosed diabetes, IGT, and IFG remain common among Maori, particularly men, the very obese, and those with greater socioeconomic disadvantage. There remains significant opportunity to reduce Maori morbidity and premature mortality through diabetes case-finding and intervention.

摘要

目的

描述毛利人群中未诊断糖尿病、糖耐量受损(IGT)和空腹血糖受损(IFG)(“血糖异常”)的患病率。

方法

“Te Wai o Rona:糖尿病预防策略”是一项针对新西兰怀卡托/湖区毛利家庭生活方式改变的试验。所有年龄≥28岁、无已知糖尿病的毛利家庭住户成员,通过初级保健、社区和媒体渠道被邀请参与。参与者被邀请进行口服葡萄糖耐量试验(OGTT)。

结果

在3817名符合条件的毛利人中,女性平均体重指数(BMI)为32.9±7.8kg/m²,男性为33.1±6.7kg/m²。未诊断糖尿病的年龄标准化患病率男性高于女性(6.5[5.8 - 7.4]%对4.2[3.6 - 4.8]%),IFG也是如此(5.4[4.7 - 6.1]%对3.0[2.3 - 3.5]%),但IGT并非如此(8.5[7.6 - 9.4]%对9.7[8.7 - 10.6]%),且不存在城乡差异。血糖异常患病率随BMI增加而升高,无明显拐点,在调整年龄、性别和BMI后,持有社区服务卡者的患病率比未持有社区服务卡者高1.33(1.11 - 1.60)倍。

结论

未诊断糖尿病、IGT和IFG在毛利人群中仍然常见,尤其是男性、极度肥胖者以及社会经济劣势较大者。通过糖尿病筛查和干预,仍有很大机会降低毛利人的发病率和过早死亡率。

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