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术中经食管超声心动图对儿童左心室辅助装置植入术中的血流动力学稳定有益。

Intraoperative transesophageal echocardiography is beneficial for hemodynamic stabilization during left ventricular assist device implantation in children.

作者信息

Scohy Thierry V, Gommers Diederik, Maat Alexander P W M, Dejong Peter L, Bogers Ad J J C, Hofland Jan

机构信息

Department of Anaesthesiology, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

Paediatr Anaesth. 2009 Apr;19(4):390-5. doi: 10.1111/j.1460-9592.2008.02917.x. Epub 2009 Jan 27.

Abstract

BACKGROUND

Mechanical circulatory support, with a left ventricular assist device (LVAD) is used in an increasing number of children for treatment of advanced heart failure as bridge-to-transplant. To date no data are available and no studies have defined the role of intraoperative transesophageal echocardiography (TEE) for hemodynamic stabilization during Centrimag Levitronix centrifugal pump implantation in children.

METHODS

Children with therapy resistant heart failure, undergoing LVAD implantation using Berlin Heart Excor pediatric cannula connected to a Levitronix Centrifumag pump, are intraoperatively monitored using an Oldelft micromultiplane TEE. Intraoperative TEE is specially used to monitor right ventricular (RV) and left ventricular (LV) function, correct position of the cannulas and response to pharmacological treatment.

RESULTS

In five consecutive patients RV function was assessed by TEE after starting LVAD Levitronix centrifugal pump. Initial RV failure presents with RV dilation and LV collapse. After titration of vasopressor and inotropic agents, RV contractility improved and thereby the filling of the LV. In one child, despite those measures the RV showed no improvement by TEE and a Levitronix right ventricular assist device to support the RV function was implanted as well. All patients could hemodynamically be stabilized before transport to the intensive care unit.

CONCLUSION

The complex interaction of the RV and LV function and correct positioning of the cannula, during LVAD implantation in children with end-stage cardiac failure is improved by simultaneous visualization of cardiac performance of both ventricles and cannula positioning by means of intraoperative multiplane TEE.

摘要

背景

越来越多的儿童使用左心室辅助装置(LVAD)进行机械循环支持,以治疗晚期心力衰竭作为移植桥梁。迄今为止,尚无可用数据,也没有研究明确术中经食管超声心动图(TEE)在儿童植入Centrimag Levitronix离心泵期间对血流动力学稳定的作用。

方法

使用连接到Levitronix Centrifumag泵的柏林心脏Excor儿科插管进行LVAD植入的难治性心力衰竭儿童,术中使用Oldelft微型多平面TEE进行监测。术中TEE专门用于监测右心室(RV)和左心室(LV)功能、插管的正确位置以及对药物治疗的反应。

结果

在连续5例患者中,启动Levitronix离心泵后通过TEE评估RV功能。初始RV衰竭表现为RV扩张和LV塌陷。在滴定血管升压药和正性肌力药物后,RV收缩力改善,从而改善了LV的充盈。在1例儿童中,尽管采取了这些措施,TEE显示RV没有改善,因此也植入了Levitronix右心室辅助装置以支持RV功能。所有患者在转运至重症监护病房之前血流动力学均得以稳定。

结论

通过术中多平面TEE同时观察两个心室的心脏功能和插管位置,可改善终末期心力衰竭儿童LVAD植入期间RV和LV功能的复杂相互作用以及插管的正确定位。

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