Kundu Shilajit D, Eggener Scott E
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Adv Urol. 2009;2009:181927. doi: 10.1155/2009/181927. Epub 2009 Jan 26.
The incidence of transitional cell carcinoma of the kidney and ureter is low and for that reason limited data exists regarding the appropriate management of regional retroperitoneal lymph nodes. Lymph node metastases have consistently been associated with an adverse prognosis. However, five-year cancer-specific survival following nephroureterectomy and lymphadenectomy for patients with lymph node involvement ranges from 0-39%, suggesting a therapeutic benefit. This review covers the primary tumor characteristics associated with lymph node involvement, imaging of the lymph nodes, as well as the rationale, role, patient selection, suggested anatomic templates, and technical considerations for lymphadenectomy.
肾和输尿管移行细胞癌的发病率较低,因此关于区域腹膜后淋巴结的适当管理的数据有限。淋巴结转移一直与不良预后相关。然而,对于有淋巴结受累的患者,肾输尿管切除术和淋巴结清扫术后的五年癌症特异性生存率为0%-39%,提示有治疗益处。本综述涵盖了与淋巴结受累相关的原发性肿瘤特征、淋巴结的影像学检查,以及淋巴结清扫术的基本原理、作用、患者选择、建议的解剖模板和技术要点。