Moss W J
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore MD, USA.
Curr Top Microbiol Immunol. 2009;330:173-89. doi: 10.1007/978-3-540-70617-5_9.
Remarkable progress has been made in reducing measles incidence and mortality as a consequence of implementing the measles mortality reduction strategy of the World Health Organization (WHO) and United Nations Children's Fund (UNICEF). The revised global measles mortality reduction goal set forth in the WHO-UNICEF Global Immunization Vision and Strategy for 2006-2015 is to reduce measles deaths by 90% by 2010 compared to the estimated 757,000 deaths in 2000. The possibility of measles eradication has been discussed for almost 40 years, and measles meets many of the criteria for eradication. Global measles eradication will face a number of challenges to achieving and sustaining high levels of vaccine coverage and population immunity, including population growth and demographic changes, conflict and political instability, and public perceptions of vaccine safety. To achieve the measles mortality reduction goal, continued progress needs to be made in delivering measles vaccines to the world's children.
由于实施了世界卫生组织(WHO)和联合国儿童基金会(UNICEF)的降低麻疹死亡率战略,在降低麻疹发病率和死亡率方面已取得显著进展。WHO-UNICEF《2006 - 2015年全球免疫远景与战略》中设定的修订后的全球降低麻疹死亡率目标是,到2010年将麻疹死亡人数比2000年估计的75.7万例减少90%。关于根除麻疹的可能性已讨论了近40年,麻疹符合许多根除标准。全球根除麻疹在实现和维持高水平疫苗接种覆盖率及人群免疫力方面将面临诸多挑战,包括人口增长和人口结构变化、冲突和政治不稳定以及公众对疫苗安全性的认知。为实现降低麻疹死亡率目标,在向全球儿童提供麻疹疫苗方面需要持续取得进展。