来自娃儿藤的C21甾体苷。

C21 steroidal glycosides from Cynanchum wallichii Wight.

作者信息

Chen Gang, Xu Nan, Pei Yue-Hu

机构信息

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

出版信息

J Asian Nat Prod Res. 2009;11(2):177-82. doi: 10.1080/10286020802619017.

DOI:10.1080/10286020802619017

PMID:19219732

Abstract

Three new C21 steroidal glycosides, characterized with rostratamine and qinyangshengenin as aglycone moiety and 2,6-dideoxy-pyranoses as component sugars, have been isolated from the roots of Cynanchum wallichii Wight. The structures of the three new C21 steroidal glycosides were elucidated as rostratamine-3-O-beta-D-oleandropyranosyl-(1 --> 4)-beta-d-cymaropyranosyl-(1 --> 4)-beta-D-cymaropyranoside, qinyangshengenin-3-O-beta-D-cymaropyranosyl-(1 --> 4)-beta-D-digitoxo-pyranoside, and qinyangshengenin-3-O-beta-D-oleandropyranosyl-(1 --> 4)-beta-D-cymaropyranosyl-(1 --> 4)-beta-D-digitoxopyranoside.

摘要

从娃儿藤（Cynanchum wallichii Wight）的根中分离出了三种新的C21甾体糖苷，其苷元部分为萝藦胺和青阳参苷元，组成糖为2,6-二脱氧吡喃糖。这三种新的C21甾体糖苷的结构被鉴定为萝藦胺-3-O-β-D-夹竹桃吡喃糖基-(1→4)-β-D-磁麻吡喃糖基-(1→4)-β-D-磁麻吡喃糖苷、青阳参苷元-3-O-β-D-磁麻吡喃糖基-(1→4)-β-D-洋地黄毒吡喃糖苷以及青阳参苷元-3-O-β-D-夹竹桃吡喃糖基-(1→4)-β-D-磁麻吡喃糖基-(1→4)-β-D-洋地黄毒吡喃糖苷。