Department of Clinical and Experimental Medicine, Clinica Medica and Vascular Diseases Center, University of Ferrara, via Savonarola 9, Ferrara, Italy.
Clin Appl Thromb Hemost. 2010 Apr;16(2):153-60. doi: 10.1177/1076029609332111. Epub 2009 Feb 16.
Acute cerebrovascular events are not randomly distributed over time but show specific temporal patterns of occurrence. However, most studies focused stroke and little is known about transient ischemic attack. This study aimed to explore the existence of a temporal pattern of transient ischemic attack and the possible influence by the most common risk factors. The analysis included all hospital admissions with the ICD9-CM code for TIA, recorded in the database of the Emilia Romagna region of Italy (1998-2006; n = 43642, mean age 76.8 +/- 11.5 years, 45.5% males). Transient ischemic attack was most frequent in autumn and winter and less common in spring and summer (P < 0.0001), with the highest number of cases in October and the lowest in February, and also most frequent on Monday (P < 0.0001). This study shows a seasonal and weekly pattern in occurrence of transient ischemic attack, independent of sex and the presence of the most common risk factors.
急性脑血管事件的发生时间并非随机分布,而是呈现出特定的时间模式。然而,大多数研究都集中在中风上,对于短暂性脑缺血发作(TIA)知之甚少。本研究旨在探讨 TIA 是否存在时间模式,以及最常见的风险因素是否可能产生影响。该分析包括意大利艾米利亚-罗马涅地区数据库中记录的所有 TIA 的 ICD9-CM 编码住院病例(1998-2006 年;n=43642,平均年龄 76.8±11.5 岁,男性占 45.5%)。TIA 最常发生在秋冬季节,而在春夏季节较少见(P<0.0001),10 月病例数最多,2 月最少,周一也最常见(P<0.0001)。本研究表明,TIA 的发生存在季节性和周性模式,与性别和最常见的风险因素无关。