快速测量全身水含量以促进老年住院患者的临床决策。
Rapid measurement of total body water to facilitate clinical decision making in hospitalized elderly patients.
作者信息
Powers James S, Choi Leena, Bitting Rhonda, Gupta Nitin, Buchowski Maciej
机构信息
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
出版信息
J Gerontol A Biol Sci Med Sci. 2009 Jun;64(6):664-9. doi: 10.1093/gerona/glp018. Epub 2009 Feb 19.
BACKGROUND
Bioelectrical impedance analysis (BIA) is a noninvasive rapid and simple bedside technique that can be used to predict total body water (TBW), extracellular water (ECW), and intracellular water (ICW) and identify altered fluid distribution following critical illness.
METHODS
An equivalence study of BIA in 32 hospitalized elderly patients was compared with reference standard dilutional measurements of deuterated water (TBW) and sodium bromide (ECW). The results were compared with anthropometric equations commonly used to predict TBW.
RESULTS
There was variability in TBW content among the participating hospitalized elderly patients. This variability was within (+/-5 L) and the percent difference between the standard and BIA was as follows: mean (range) -4.1% (-18.5 to 11.2). BIA reliably predicted TBW and ECW in individual participants, whereas standard prediction equations uniformly over- or underestimated TBW in individuals and whole group population.
CONCLUSION
TBW in hospitalized elderly patients can be estimated noninvasively by bedside BIA. Standardized anthropometric equations have to be used with caution in this population.
背景
生物电阻抗分析（BIA）是一种非侵入性的快速简便的床边技术，可用于预测总体水（TBW）、细胞外液（ECW）和细胞内液（ICW），并识别危重病后体液分布的变化。
方法
对32例住院老年患者的BIA进行等效性研究，并与氘水（TBW）和溴化钠（ECW）的参考标准稀释测量值进行比较。将结果与常用于预测TBW的人体测量方程进行比较。
结果
参与研究的住院老年患者的TBW含量存在差异。这种差异在（±5L）范围内，标准测量值与BIA之间的百分比差异如下：平均值（范围）-4.1%（-18.5至11.2）。BIA能够可靠地预测个体参与者的TBW和ECW，而标准预测方程在个体和整个群体中均一致高估或低估了TBW。
结论
住院老年患者的TBW可通过床边BIA进行非侵入性估计。在该人群中使用标准化人体测量方程时需谨慎。
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