星形细胞瘤发作期氟代脱氧葡萄糖正电子发射断层显像中的交叉小脑灌注过度

Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma.

作者信息

Lin Michael, Smith Tracy, Beran Roy G

机构信息

Department of PET and Nuclear Medicine, Liverpool Hospital, University of New South Wales, 1 Elizabeth Drive, Liverpool, New South Wales 2170, Australia.

出版信息

J Clin Neurosci. 2009 Apr;16(4):603-4. doi: 10.1016/j.jocn.2008.07.073. Epub 2009 Feb 23.

DOI:10.1016/j.jocn.2008.07.073

PMID:19231196

Abstract

Crossed cerebellar hyperperfusion (CCH) is a rare phenomenon and reflects the close anatomical and functional relationship between the frontal brain region and its mediated remote effect on the contralateral cerebellum via the corticopontocerebellar pathway. Although it is well documented on cerebral single photon emission tomography (SPECT) in patients with epilepsy, it is rarely observed in seizures originating from brain tumours. We report a 41-y-old man who whilst undergoing (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for investigation of suspected glioma, developed a generalized seizure. The scan performed shortly after seizure onset demonstrated intense metabolic activity in the right superior frontal lobe and in the contralateral cerebellar hemisphere consistent with CCH.

摘要

交叉性小脑灌注增强（CCH）是一种罕见现象，反映了额叶脑区与其通过皮质脑桥小脑通路对侧小脑介导的远程效应之间密切的解剖和功能关系。尽管在癫痫患者的脑单光子发射断层扫描（SPECT）中有充分记录，但在源自脑肿瘤的癫痫发作中很少观察到。我们报告一名41岁男性，在接受（18）F-氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）以调查疑似神经胶质瘤时发生了全身性癫痫发作。癫痫发作开始后不久进行的扫描显示右上额叶和对侧小脑半球有强烈的代谢活动，符合交叉性小脑灌注增强。