Folgado J, Fernandes P R, Jacobs C R, Pellegrini V D
Instituto Superior Tecnico, Technical University of Lisbon, Lisbon, Portugal.
Comput Methods Biomech Biomed Engin. 2009 Apr;12(2):135-45. doi: 10.1080/10255840903081123.
This work presents a computational model for the concurrent study of bone remodelling and ingrowth around cementless femoral stems in total hip arthroplasty. It is assumed that biological fixation depends upon the magnitude of relative displacement at the bone-stem interface as well as an ongoing updating of interface conditions during the remodelling process. The remodelling model determines the distribution of bone density by producing the stiffest structure for a given set of biological conditions at the point of equilibrium in bone turnover. Changes in bone density and patterns of ingrowth are compared for different stem geometries, materials and lengths of surface coating. Patterns of bone ingrowth on the tapered stem were independent of extent of porous coating, while ingrowth varied with the length of coating on the cylindrical stem. This model integrates knowledge of under what mechanical conditions bone ingrowth occurs on prosthetic stem surfaces with remodelling behaviour over time.
这项工作提出了一个计算模型,用于同时研究全髋关节置换术中非骨水泥股骨柄周围的骨重塑和骨长入情况。假定生物固定取决于骨-柄界面处相对位移的大小以及重塑过程中界面条件的持续更新。重塑模型通过在骨转换平衡时为给定的一组生物学条件生成最坚固的结构来确定骨密度分布。针对不同的柄几何形状(stem geometries)、材料和表面涂层长度,比较了骨密度变化和骨长入模式。锥形柄上的骨长入模式与多孔涂层的范围无关,而圆柱形柄上的骨长入则随涂层长度而变化。该模型整合了关于在何种力学条件下骨在假体柄表面发生长入以及随时间的重塑行为这两方面的知识。