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泰瑟X26电击枪在理想人体心脏轴线上应用的超声心动图评估。

Echocardiographic evaluation of a TASER-X26 application in the ideal human cardiac axis.

作者信息

Ho Jeffrey D, Dawes Donald M, Reardon Robert F, Lapine Anne L, Dolan Benjamin J, Lundin Erik J, Miner James R

机构信息

Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, MN, USA.

出版信息

Acad Emerg Med. 2008 Sep;15(9):838-44. doi: 10.1111/j.1553-2712.2008.00201.x.

Abstract

OBJECTIVES

TASER electronic control devices (ECDs) are used by law enforcement to subdue aggressive persons. Some deaths temporally proximate to their use have occurred. There is speculation that these devices can cause dangerous cardiac rhythms. Swine research supports this hypothesis and has reported significant tachyarrhythmias. It is not known if this occurs in humans. The objective of this study was to determine the occurrence of tachyarrhythmias in human subjects subjected to an ECD application.

METHODS

This was a prospective, nonblinded study. Human volunteers underwent limited echocardiography before, during, and after a 10-second TASER X26 ECD application with preplaced thoracic electrodes positioned in the upper right sternal border and the cardiac apex. Images were analyzed using M-mode through the anterior leaflet of the mitral valve for evidence of arrhythmia. Heart rate (HR) and the presence of sinus rhythm were determined. Data were analyzed using descriptive statistics.

RESULTS

A total of 34 subjects were enrolled. There were no adverse events reported. The mean HR prior to starting the event was 108.7 beats/min (range 65 to 146 beats/min, 95% CI = 101.0 to 116.4 beats/min). During the ECD exposure, the mean HR was 120.1 beats/min (range 70 to 158 beats/min, 95% CI = 112.2 to 128.0 beats/min) and a mean of 94.1 beats/min (range 55 to 121 beats/min, 95% CI = 88.4 to 99.7 beats/min) at 1 minute after ECD exposure. Sinus rhythm was clearly demonstrated in 21 (61.7%) subjects during ECD exposure (mean HR 121.4 beats/min; range 75 to 158 beats/min, 95% CI = 111.5 to 131.4). Sinus rhythm was not clearly demonstrated in 12 subjects due to movement artifact (mean HR 117.8 beats/min, range 70 to 152 beats/min, 95% CI = 102.8 to 132.8 beats/min).

CONCLUSIONS

A 10-second ECD exposure in an ideal cardiac axis application did not demonstrate concerning tachyarrhythmias using human models. The swine model may have limitations when evaluating ECD technology.

摘要

目的

执法部门使用泰瑟电子控制设备(ECD)制服具有攻击性的人员。在其使用后不久发生了一些死亡事件。有人猜测这些设备可能会导致危险的心律。猪的研究支持这一假设,并报告了显著的快速心律失常。目前尚不清楚这在人类中是否会发生。本研究的目的是确定接受ECD应用的人类受试者中快速心律失常的发生情况。

方法

这是一项前瞻性、非盲法研究。人类志愿者在使用泰瑟X26 ECD持续10秒之前、期间和之后接受有限的超声心动图检查,预先放置的胸部电极位于胸骨右缘上方和心尖处。通过二尖瓣前叶使用M型分析图像以寻找心律失常的证据。确定心率(HR)和窦性心律的存在。使用描述性统计分析数据。

结果

共招募了34名受试者。未报告不良事件。事件开始前的平均心率为108.7次/分钟(范围65至146次/分钟,95%置信区间=101.0至116.4次/分钟)。在ECD暴露期间,平均心率为120.1次/分钟(范围70至158次/分钟,95%置信区间=112.2至128.0次/分钟),在ECD暴露后1分钟时平均为94.1次/分钟(范围55至121次/分钟,95%置信区间=88.4至99.7次/分钟)。在ECD暴露期间,21名(61.7%)受试者明确显示窦性心律(平均心率121.4次/分钟;范围75至158次/分钟,95%置信区间=111.5至131.4)。由于运动伪影,12名受试者未明确显示窦性心律(平均心率117.8次/分钟,范围70至152次/分钟,95%置信区间=102.8至132.8次/分钟)。

结论

在理想的心轴应用中,10秒的ECD暴露在人体模型中未显示出令人担忧的快速心律失常。在评估ECD技术时,猪模型可能存在局限性。

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