Liu Lenna L, Yi Joyce P, Beyer Jennifer, Mayer-Davis Elizabeth J, Dolan Lawrence M, Dabelea Dana M, Lawrence Jean M, Rodriguez Beatriz L, Marcovina Santica M, Waitzfelder Beth E, Fujimoto Wilfred Y
Department of Pediatrics, Seattle Children's Hospital, Seattle, Washington, USA.
Diabetes Care. 2009 Mar;32 Suppl 2(Suppl 2):S133-40. doi: 10.2337/dc09-S205.
Given limited reports on diabetes among U.S. Asian and Pacific Islander youth, we describe the clinical characteristics, incidence, and prevalence of diabetes among Asian, Pacific Islander, and mixed Asian-Pacific Islander youth.
Data were collected from 245 Asian, Pacific Islander, and Asian-Pacific Islander participants in the SEARCH for Diabetes in Youth Study, a population-based study of diabetes in youth (aged <20 years). Additionally, we estimated the incidence and prevalence of type 1 and type 2 diabetes for Asian, Pacific Islander, and Asian-Pacific Islander youth combined.
Most participants with type 2 diabetes were obese (range Asian 71% to Pacific Islander 100%) with mean BMI >33 kg/m(2). In those with type 1 diabetes, Pacific Islanders were more likely to be obese, with a mean BMI of 26 vs. 20 kg/m(2) for Asian and Asian-Pacific Islander youth (P < 0.0001). The incidence of type 1 diabetes for youth aged 0-9 years was 6.4 per 100,000 person-years and 7.4 per 100,000 person-years for youth aged 10-19 years. The incidence of type 2 diabetes was 12.1 per 100,000 person-years for youth aged 10-19 years.
While Asian and Asian-Pacific Islanders with type 1 and type 2 diabetes had lower mean BMIs than Pacific Islanders, all Asian, Pacific Islander, and Asian-Pacific Islanders with type 2 diabetes had mean BMIs above adult ethnicity-specific definitions of obesity. While the majority of Asian, Pacific Islander, and Asian-Pacific Islander youth had type 1 diabetes, older Asian, Pacific Islander, and Asian-Pacific Islander youth (aged 10-19 years) have an incidence of type 2 diabetes almost double that of type 1 diabetes. Public health efforts to prevent type 2 diabetes and obesity in Asian, Pacific Islander, and Asian-Pacific Islander adolescents are needed.
鉴于关于美国亚裔和太平洋岛民青少年糖尿病的报道有限,我们描述了亚裔、太平洋岛民及亚裔与太平洋岛民混血青少年糖尿病的临床特征、发病率和患病率。
数据来自“青少年糖尿病研究(SEARCH)”中的245名亚裔、太平洋岛民及亚裔与太平洋岛民混血参与者,该研究是一项基于人群的青少年(年龄<20岁)糖尿病研究。此外,我们估算了亚裔、太平洋岛民及亚裔与太平洋岛民混血青少年1型和2型糖尿病的发病率和患病率。
大多数2型糖尿病参与者肥胖(亚裔范围为71%至太平洋岛民为100%),平均体重指数>33kg/m²。在1型糖尿病患者中,太平洋岛民更易肥胖,其平均体重指数为26kg/m²,而亚裔及亚裔与太平洋岛民混血青少年为20kg/m²(P<0.0001)。0至9岁青少年1型糖尿病发病率为每10万人年6.4例,10至19岁青少年为每10万人年7.4例。10至19岁青少年2型糖尿病发病率为每10万人年12.1例。
虽然患1型和2型糖尿病的亚裔及亚裔与太平洋岛民的平均体重指数低于太平洋岛民,但所有患2型糖尿病的亚裔、太平洋岛民及亚裔与太平洋岛民的平均体重指数均高于按成人种族划分的肥胖定义。虽然大多数亚裔、太平洋岛民及亚裔与太平洋岛民青少年患1型糖尿病,但年龄较大的亚裔、太平洋岛民及亚裔与太平洋岛民青少年(10至19岁)2型糖尿病发病率几乎是1型糖尿病的两倍。需要开展公共卫生工作以预防亚裔、太平洋岛民及亚裔与太平洋岛民青少年的2型糖尿病和肥胖症。