鞘膜恶性间皮瘤中肾母细胞瘤-1蛋白和CD138的表达

Expression of Wilms tumor-1 protein and CD 138 in malignant mesothelioma of the tunica vaginalis.

作者信息

Al-Salam Suhail, Hammad Fayez T, Salman Muwafak A, AlAshari Mouied

机构信息

Department of Pathology, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE.

出版信息

Pathol Res Pract. 2009;205(11):797-800. doi: 10.1016/j.prp.2009.01.012. Epub 2009 Feb 27.

DOI:10.1016/j.prp.2009.01.012

PMID:19250757

Abstract

Malignant mesothelioma (MM) of the tunica vaginalis is a very rare tumor which can be difficult to diagnose histologically. We report an 83-year-old patient with MM of tunica vaginalis of the left testis. To the best of our knowledge, this is the first reported case of MM of the tunica vaginalis expressing Wilms tumor-1 protein, CD138, the expression of which could help in confirming the histopathological diagnosis and in targeting therapy.

摘要

睾丸鞘膜恶性间皮瘤（MM）是一种非常罕见的肿瘤，其组织学诊断可能具有挑战性。我们报告一例83岁患有左侧睾丸鞘膜MM的患者。据我们所知，这是首例报道的表达肾母细胞瘤-1蛋白、CD138的睾丸鞘膜MM病例，其表达有助于确诊组织病理学诊断并指导靶向治疗。