血管内大B细胞淋巴瘤累及腹部皮下组织：一例报告及文献复习
Intravascular large B-cell lymphoma with involvement of the abdominal subcutis: a case report and literature review.
作者信息
Yin Wenjuan, Li Min, Gao Zifen, Huang Fanzhou, Da Jiping, Liu Cuiling
机构信息
Department of Pathology, Peking University Health Science Center, 100191, Beijing, China.
Department of Hematology, Peking University China-Japan Friendship Hospital, 100029, Beijing, China.
出版信息
Int J Hematol. 2009 Apr;89(3):348-351. doi: 10.1007/s12185-009-0262-0. Epub 2009 Mar 3.
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL). It commonly presents with a variety of symptoms due to occlusion of small vessels by tumor cells in different organ systems. Clinically patients may present with generalized symptoms such as fever and malaise. In western patients, there is a 'cutaneous variant' of IVLBCL, which demonstrates cutaneous involvement only. However, Asian patients show hemophagocytosis, which is typical of the 'Asian variant'. Here we report a case of IVLBCL in a Chinese individual who presented with a huge mass in the subcutis of the abdomen.
血管内大B细胞淋巴瘤（IVLBCL）是弥漫性大B细胞淋巴瘤（DLBCL）的一种罕见亚型。由于肿瘤细胞阻塞不同器官系统的小血管，它通常会出现多种症状。临床上，患者可能会出现发热和不适等全身症状。在西方患者中，有一种IVLBCL的“皮肤变异型”，仅表现为皮肤受累。然而，亚洲患者会出现噬血细胞现象，这是“亚洲变异型”的典型表现。在此，我们报告一例中国患者的IVLBCL病例，该患者腹部皮下出现巨大肿块。
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