West Catharine M L, Davidson Susan E
Academic Department of Radiation Oncology, The University of Manchester, UK.
Curr Opin Support Palliat Care. 2009 Mar;3(1):36-40. doi: 10.1097/SPC.0b013e328325d18d.
To review the use of measurement tools for reporting gastrointestinal toxicity in radiation oncology to highlight recent findings of potential interest to those involved in the treatment of tumors in the pelvis, assessment of survivorship issues or management of bowel effects.
Multiple measurement tools are being used in radiation oncology studies involving both clinician and patient-reported outcomes. The increasing availability of accurate data on radiation doses and dose-volumes to normal tissues is enabling identification of critical areas where dose should be reduced to minimize organ damage.
Measurement tools for gastrointestinal symptoms are important to highlight therapeutic benefit for the expanding investigations of treatment intensification approaches and methods for toxicity reduction. The increasing use of the CTCAEv3 scales is a step forward, but further research is required to refine the system and improve its ease of use within routine clinical practice.
回顾放射肿瘤学中用于报告胃肠道毒性的测量工具，以突出近期对骨盆肿瘤治疗、生存问题评估或肠道效应管理相关人员可能感兴趣的研究结果。
在涉及临床医生和患者报告结果的放射肿瘤学研究中，正在使用多种测量工具。关于辐射剂量和正常组织剂量体积的准确数据越来越容易获取，这使得能够识别应降低剂量以尽量减少器官损伤的关键区域。
胃肠道症状的测量工具对于突出强化治疗方法和降低毒性方法的扩展研究的治疗益处很重要。CTCAEv3量表的使用增加是向前迈出的一步，但需要进一步研究来完善该系统并提高其在常规临床实践中的易用性。
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