对单纯疱疹病毒2型血清阴性孕妇的单纯疱疹病毒检测伴侣的接受情况。
The acceptance of HSV-testing partners of HSV-2 seronegative pregnant women.
作者信息
Gardella Carolyn, Krantz Elizabeth, Daruthayan Constance, Drolette Linda, Corey Lawrence, Wald Anna
机构信息
Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA.
出版信息
Sex Transm Dis. 2009 Apr;36(4):211-5. doi: 10.1097/OLQ.0b013e318193ca40.
OBJECTIVES
To estimate the acceptance of HSV testing partners of HSV seronegative pregnant women and identify associated factors.
STUDY DESIGN
Consecutive women identified as HSV-2 seronegative during routine testing in pregnancy were asked to invite their partners for HSV testing to identify serodiscordance. Logistic regression identified factors associated with partner testing.
RESULTS
Between 2001 to 2006, 315 women enrolled (28% of those approached) and 242 (77%) partners were tested. Married couples were most likely to be tested [adjusted odds ratio (aOR) 7.72, 95% CI: 2.47-24.15]. Partners of black women (aOR 0.17, 95% CI: 0.04-0.71), and those with at least a college degree (aOR 0.43, 95% CI: 0.19-0.98) were less likely to be tested.
CONCLUSIONS
In this population, partner testing among HSV-2 seronegative women was feasible which supports further study to determine if identification of partners who pose a potential risk of HSV infection during pregnancy is an effective approach to reduce HSV acquisition in pregnant women.
目的
评估单纯疱疹病毒（HSV）血清学阴性孕妇的性伴侣对HSV检测的接受程度，并确定相关因素。
研究设计
在孕期常规检测中被确定为HSV - 2血清学阴性的连续入选女性，被要求邀请其性伴侣进行HSV检测，以确定血清学不一致情况。逻辑回归分析确定与性伴侣检测相关的因素。
结果
在2001年至2006年期间，315名女性入选（占被邀请者的28%），242名（77%）性伴侣接受了检测。已婚夫妇接受检测的可能性最大[调整优势比（aOR）7.72，95%置信区间（CI）：2.47 - 24.15]。黑人女性的性伴侣（aOR 0.17，95% CI：0.04 - 0.71）以及至少拥有大学学位的女性的性伴侣（aOR 0.43，95% CI：0.19 - 0.98）接受检测的可能性较小。
结论
在这一人群中，HSV - 2血清学阴性女性的性伴侣检测是可行的，这支持进一步研究以确定识别孕期存在HSV感染潜在风险的性伴侣是否是降低孕妇HSV感染率的有效方法。
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