Vcelák J, Tóth L, Slégl M, Suman R, Majernícek M
Ortopedická klinika 1.LF UK a IPVZ FN Na Bulovce, Praha.
Acta Chir Orthop Traumatol Cech. 2009 Feb;76(1):54-9.
PURPOSE OF THE STUDY The surgical treatment of osteoporotic vertebral body fractures is associated with many complications. Vertebroplasty (VP) and kyphoplasty (KP) are minimally invasive procedures allowing us to strengthen the vertebral body and thus stabilize it. The aim of this non-randomized study is to evaluate a group of patients treated by VP and KP procedures and to discuss related risks. MATERIAL Between September 2005 and October 2007, a total of 32 patients (37 vertebrae) were treated by the VP and KP techniques. Vertebroplasty was used in 21 and kyphoplasty in 11 patients. In this initial group, four patients were excluded from evaluation because of a tumour aetiology of the fracture. The remaining 28 patients who had an osteoporotic vertebral body fracture verified by CT scan findings were followed up and evaluated. METHODS The evaluation was based on modified Oswestry disability index (ODI) and visual analogue scale (VAS) scores recorded at 6 weeks, 3 and 6 months and 1 year postoperatively. Cement leakage detected by X-ray was assessed by means of the classification used by Yeom et al. and, at the same time, the occurrence of adjacent vertebral fracture, if any, was detected by 1 year after surgery. RESULTS Radiographic cement leakage was found in eight patients (21.6%), with clinical manifestation in two (5.4%). One had an incomplete motor lesion due to cement leakage into the spinal column, and the other had pulmonary embolism due to cement leakage into the mediastinum. The whole group showed marked improvement in clinical condition, as assessed by the ODI. When expressed as per cent, the average ODI was 57% pre- and 15.7 % post-operatively. All patients reported pain relief in the affected spine. The average VAS score of 8.1 pre-operatively decreased to an average of 2.6 post-operatively. There were no radiographic findings of adjacent vertebral body fracture. DISCUSSION Vertebroplasty and kyphoplasty are currently used to treat osteoporotic vertebral fracture. Their advantages include an immediate stabilization of the vertebra by cement solidification, possibility of percutaneous application under local anaesthesia, and early patient mobilization without any external fixation. However, when evaluating these techniques, safety of the surgical procedure should be taken into consideration. The most frequent risk is cement leakage. CONCLUSIONS Vertebroplasty and kyphoplasty can, under strict adherence to the operative protocol, be an effective approach to the treatment of osteoporotic vertebral body fracture. It permits early mobilization of the patient without the necessity of external fixation. Key words: vertebroplasty, kyphoplasty, osteoporotic spine fracture, osteoporosis.
研究目的 骨质疏松性椎体骨折的外科治疗伴有许多并发症。椎体成形术(VP)和后凸成形术(KP)是微创手术,可使我们强化椎体并使其稳定。这项非随机研究的目的是评估一组接受VP和KP手术治疗的患者,并探讨相关风险。
材料 在2005年9月至2007年10月期间,共有32例患者(37个椎体)接受了VP和KP技术治疗。21例患者采用椎体成形术,11例患者采用后凸成形术。在这一初始组中,4例患者因骨折的肿瘤病因被排除在评估之外。其余28例经CT扫描结果证实患有骨质疏松性椎体骨折的患者接受了随访和评估。
方法 评估基于术后6周、3个月、6个月和1年记录的改良Oswestry功能障碍指数(ODI)和视觉模拟量表(VAS)评分。通过X射线检测到的骨水泥渗漏采用Yeom等人使用的分类方法进行评估,同时在术后1年检测是否发生相邻椎体骨折(如有)。
结果 8例患者(21.6%)发现影像学骨水泥渗漏,2例(5.4%)有临床表现。1例因骨水泥渗漏至脊柱导致不完全性运动障碍,另1例因骨水泥渗漏至纵隔导致肺栓塞。根据ODI评估,整个组的临床状况有显著改善。以百分比表示,术前平均ODI为57%,术后为15.7%。所有患者均报告患部脊柱疼痛缓解。术前平均VAS评分为8.1,术后降至平均2.6。未发现相邻椎体骨折的影像学表现。
讨论 椎体成形术和后凸成形术目前用于治疗骨质疏松性椎体骨折。它们的优点包括通过骨水泥固化立即稳定椎体、可在局部麻醉下经皮应用以及患者无需任何外固定即可早期活动。然而,在评估这些技术时,应考虑手术过程的安全性。最常见的风险是骨水泥渗漏。
结论 在严格遵守手术方案的情况下,椎体成形术和后凸成形术可以成为治疗骨质疏松性椎体骨折的有效方法。它允许患者早期活动,无需外固定。
椎体成形术;后凸成形术;骨质疏松性脊柱骨折;骨质疏松症