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使用脱细胞真皮同种异体移植物进行肌腱置入的韧带重建术治疗拇指腕掌关节关节炎。

Ligament reconstruction with tendon interposition using an acellular dermal allograft for thumb carpometacarpal arthritis.

作者信息

Kokkalis Zinon T, Zanaros George, Sotereanos Dean G

机构信息

Department of Orthopaedic Surgery, Hand & Upper Extremity Surgery, Allegheny General Hospital, Pittsburgh, PA 15212, USA.

出版信息

Tech Hand Up Extrem Surg. 2009 Mar;13(1):41-6. doi: 10.1097/BTH.0b013e31818be857.

Abstract

Ligament reconstruction tendon interposition arthroplasty is currently the preferred technique for carpometacarpal joint arthritis of the thumb by most surgeons. Despite its efficacy, morbidity has been associated with the harvest of the flexor carpi radialis tendon. Using an allograft as material for arthroplasty, donor site morbidity is avoided. In this report, we present our surgical technique to perform ligament reconstruction tendon interposition arthroplasty using an acellular dermal matrix allograft (GraftJacket) in patients with Eaton stages II, III, and IV symptomatic first carpometacarpal arthritis.One hundred thumbs with trapeziometacarpal osteoarthritis underwent surgical treatment using GraftJacket allograft instead of the flexor carpi radialis tendon autograft. Each patient was followed for a minimum of 12 months. The surgical procedure included trapezial excision and identification of the flexor carpi radialis. The allograft was cut to create a 15-cm strip. The ligament reconstruction was performed by passing the strip around the flexor carpi radialis tendon and suturing it to the base of the thumb metacarpal base through an intramedullary drill hole. The remaining portion of the allograft was fashioned as an interposition mass (anchovy) and interposed between the scaphoid and the base of the first metacarpal.All but 1 patient experienced significant improvement in his or her pain scale rating and grip and pinch strengths. Outcomes from this study compare very favorably with those of other series. No patients experienced a foreign body reaction or infection in this series. We believe that the use of an acellular dermal allograft for both ligament reconstruction and tendon interposition provides a safe and an effective alternative technique for the treatment of advanced first carpometacarpal arthritis.

摘要

韧带重建肌腱植入关节成形术目前是大多数外科医生治疗拇指腕掌关节关节炎的首选技术。尽管其疗效显著,但桡侧腕屈肌腱取材存在一定的并发症。使用同种异体移植物作为关节成形术的材料,可以避免供体部位的并发症。在本报告中,我们介绍了使用脱细胞真皮基质同种异体移植物(GraftJacket)对伊顿II、III和IV期有症状的第一腕掌关节炎患者进行韧带重建肌腱植入关节成形术的手术技术。

100例患有大多角骨-第一掌骨关节骨关节炎的拇指接受了使用GraftJacket同种异体移植物而非自体桡侧腕屈肌腱的手术治疗。每位患者至少随访12个月。手术过程包括大多角骨切除和桡侧腕屈肌的识别。将同种异体移植物切成15厘米长的条带。通过将条带绕过桡侧腕屈肌腱并通过髓内钻孔将其缝合到拇指掌骨基底来进行韧带重建。同种异体移植物的其余部分制成植入块(凤尾鱼状)并置于舟骨和第一掌骨基底之间。

除1例患者外,所有患者的疼痛评分、握力和捏力均有显著改善。本研究的结果与其他系列研究相比非常有利。该系列中没有患者出现异物反应或感染。我们认为,使用脱细胞真皮同种异体移植物进行韧带重建和肌腱植入为治疗晚期第一腕掌关节炎提供了一种安全有效的替代技术。

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