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柬埔寨西部地区的植物中毒暴发,2005 年。

Plant poisoning outbreak in the western area of Cambodia, 2005.

机构信息

Epidemiology and Public Health Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.

出版信息

Trans R Soc Trop Med Hyg. 2009 Sep;103(9):949-51. doi: 10.1016/j.trstmh.2009.01.022. Epub 2009 Mar 10.

Abstract

An outbreak investigation was conducted during February-March 2005 to determine the cause of several sudden deaths occurring in Pailin Province, Cambodia. Sixty-seven patients presented with non-febrile poisoning-like symptoms and 15 died of coma, including 53% children under 10 years old. Symptoms included sore throat (92%), sore lips (73%), swollen tongue (54%) and gastrointestinal signs (41%). A plant locally called prik was the source of poisoning (97.0 vs. 28.7%, odds ratio 74.3, P<0.001). Patients may have confused the edible Melientha suavis Pierre with Urobotrya siamensis Hiepko, both from the Opiliaceae family. This was the first report of Urobotrya poisoning and its clinical manifestations.

摘要

2005 年 2 月至 3 月期间开展了一次暴发调查,以确定柬埔寨柏威夏省发生的几起突然死亡事件的原因。67 名患者出现非发热性中毒样症状,15 人死于昏迷,其中 53%为 10 岁以下儿童。症状包括喉咙痛(92%)、嘴唇疼痛(73%)、舌头肿胀(54%)和胃肠道症状(41%)。一种当地称为 prik 的植物是中毒的源头(97.0%比 28.7%,比值比 74.3,P<0.001)。患者可能将食用的 Melientha suavis Pierre 与 Opiliaceae 科的 Urobotrya siamensis Hiepko 混淆。这是首次报告 Urobotrya 中毒及其临床表现。

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